4E90

Human phosphodiesterase 9 in complex with inhibitors

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-BM
Synchrotron site	APS
Beamline	17-BM
Wavelength(s)	1.0
Spacegroup name	P 41 21 2
Unit cell lengths	103.579, 103.579, 270.214
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	39.000 - 2.500
R-factor	0.1932
Rwork	0.192
R-free	0.21600
Structure solution method	FOURIER SYNTHESIS
RMSD bond length	0.009
RMSD bond angle	0.990
Refinement software	BUSTER (2.11.2)

Data quality characteristics

	Overall
Low resolution limit [Å]	48.360
High resolution limit [Å]	2.500
Rmerge	0.150
Number of reflections	51996
Completeness [%]	99.9

Crystallization Conditions

crystal ID	method	pH	temperature	details
1