4UMT
Structure of MELK in complex with inhibitors
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE ID29 |
| Synchrotron site | ESRF |
| Beamline | ID29 |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2010-06-16 |
| Detector | ADSC CCD |
| Spacegroup name | P 31 2 1 |
| Unit cell lengths | 103.274, 103.274, 64.887 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 89.440 - 1.980 |
| R-factor | 0.21442 |
| Rwork | 0.213 |
| R-free | 0.23644 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.011 |
| RMSD bond angle | 1.364 |
| Data reduction software | XDS |
| Data scaling software | SCALA |
| Refinement software | REFMAC (5.8.0064) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 89.990 |
| High resolution limit [Å] | 1.980 |
| Rmerge | 0.040 |
| Number of reflections | 28321 |
| <I/σ(I)> | 2.4 |
| Completeness [%] | 99.1 |
| Redundancy | 3.5 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
