4U5J

C-Src in complex with Ruxolitinib

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALS BEAMLINE 5.0.2
Synchrotron site	ALS
Beamline	5.0.2
Temperature [K]	93
Detector technology	CCD
Collection date	2014-01-28
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.987
Spacegroup name	P 1
Unit cell lengths	42.107, 63.228, 73.989
Unit cell angles	79.27, 89.27, 90.29

Refinement procedure

Resolution	43.398 - 2.260
R-factor	0.1992
Rwork	0.197
R-free	0.23580
RMSD bond length	0.009
RMSD bond angle	1.273
Refinement software	PHENIX ((phenix.refine: 1.8.4_1496))

Data quality characteristics

	Overall
Low resolution limit [Å]	50.000
High resolution limit [Å]	2.260
Number of reflections	34648
<I/σ(I)>	15.9
Completeness [%]	97.3
Redundancy	3.5

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	PEG 4000