4JLX

Structure of porcine cyclic GMP-AMP synthase (cGAS)

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X06SA
Synchrotron site	SLS
Beamline	X06SA
Detector technology	PIXEL
Collection date	2012-03-27
Detector	PSI PILATUS 6M
Wavelength(s)	1.00665
Spacegroup name	C 2 2 21
Unit cell lengths	47.402, 118.014, 142.599
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	45.458 - 2.004
R-factor	0.1894
Rwork	0.188
R-free	0.21470
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.008
RMSD bond angle	1.066
Refinement software	PHENIX ((phenix.refine: 1.8.1_1168))

Data quality characteristics

	Overall
Low resolution limit [Å]	47.500
High resolution limit [Å]	2.000
Number of reflections	51611

Crystallization Conditions

crystal ID	method	pH	temperature	details
1