4HVP

Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 Angstroms resolution

Experimental procedure

Spacegroup name	P 21 21 21
Unit cell lengths	51.700, 59.200, 62.450
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 2.250 *
R-factor	0.176
RMSD bond length	0.019
RMSD bond angle	0.067
Refinement software	PROLSQ

Data quality characteristics

	Overall
High resolution limit [Å]	2.250 *
Rmerge	0.068 *
Total number of observations	55569 *
Number of reflections	7943 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	5.4 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	sodium acetate	60 (%)
2	1	reservior	ammonium sulfate	20mM