4EYW

Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	CCD
Collection date	2006-11-24
Detector	MARMOSAIC 225 mm CCD
Wavelength(s)	0.97200
Spacegroup name	P 42 21 2
Unit cell lengths	148.144, 148.144, 192.070
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	45.983 - 1.885
R-factor	0.1739
Rwork	0.173
R-free	0.19720
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	IN-HOUSE MODEL
RMSD bond length	0.007
RMSD bond angle	1.033
Data reduction software	DENZO
Data scaling software	SADABS
Phasing software	PHASER
Refinement software	PHENIX ((phenix.refine: dev_1032))

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	45.983	1.980
High resolution limit [Å]	1.880	1.880
Rmerge	0.096	0.739
Number of reflections	170100
<I/σ(I)>	14.42	2.59
Completeness [%]	99.3	95.9
Redundancy	7.2	4.7

Crystallization Conditions

crystal ID	method	pH	temperature	details
1