4D2T
Structure of MELK in complex with inhibitors
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2009-09-22 |
| Detector | RIGAKU SATURN |
| Spacegroup name | P 1 |
| Unit cell lengths | 66.526, 75.410, 79.736 |
| Unit cell angles | 86.03, 69.05, 90.03 |
Refinement procedure
| Resolution | 48.540 - 2.700 |
| R-factor | 0.2732 |
| Rwork | 0.270 |
| R-free | 0.34000 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.010 |
| RMSD bond angle | 1.110 |
| Data reduction software | d*TREK |
| Data scaling software | d*TREK |
| Refinement software | BUSTER (2.11.5) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 48.500 |
| High resolution limit [Å] | 2.700 |
| Rmerge | 0.070 |
| Number of reflections | 39601 |
| <I/σ(I)> | 5.9 |
| Completeness [%] | 93.1 |
| Redundancy | 1.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
