3WZD
KDR in complex with ligand lenvatinib
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Detector | PSI PILATUS 6M |
| Wavelength(s) | 1.00003 |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 42.334, 84.225, 46.892 |
| Unit cell angles | 90.00, 100.20, 90.00 |
Refinement procedure
| Resolution | 46.150 - 1.570 |
| R-factor | 0.18372 |
| Rwork | 0.181 |
| R-free | 0.21188 |
| RMSD bond length | 0.012 |
| RMSD bond angle | 1.580 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Refinement software | REFMAC (5.5.0109) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 46.150 | 1.820 |
| High resolution limit [Å] | 1.570 | 1.570 |
| Rmerge | 0.060 | 0.444 |
| Number of reflections | 44907 | |
| Completeness [%] | 99.5 | 99.7 |
| Redundancy | 4.2 | 4.2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 9.5 | 277 | 0.1M CHES,5-20% PEG 8000, pH 9.5, VAPOR DIFFUSION, temperature 277K |
