2V0Z

Crystal Structure of Renin with Inhibitor 10 (Aliskiren)

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	ENRAF-NONIUS FR591
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	1995-01-01
Detector	MARRESEARCH
Spacegroup name	P 21 3
Unit cell lengths	141.600, 141.600, 141.600
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	40.000 - 2.200
R-factor	0.205
Rwork	0.205
R-free	0.26600
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.011
RMSD bond angle	2.030
Data reduction software	MARXDS
Data scaling software	MARSCALE
Refinement software	X-PLOR

Data quality characteristics

	Overall
Low resolution limit [Å]	40.000
High resolution limit [Å]	2.200
Rmerge	0.060
Number of reflections	46674
Completeness [%]	97.0
Redundancy	4.01

Crystallization Conditions

crystal ID	method	pH	temperature	details
1		3		pH 3.00