2MIP

CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) TYPE 2 PROTEASE IN COMPLEX WITH A REDUCED AMIDE INHIBITOR AND COMPARISON WITH HIV-1 PROTEASE STRUCTURES

Experimental procedure

Spacegroup name	P 43
Unit cell lengths	55.100, 55.100, 138.900
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	6.000 - 2.200
R-factor	0.176
Rwork	0.176
RMSD bond length	0.018
RMSD bond angle	2.810
Phasing software	X-PLOR
Refinement software	TNT

Data quality characteristics

	Overall
High resolution limit [Å]	2.200 *
Rmerge	0.066 *
Total number of observations	85564 *
Number of reflections	18007 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	7.4 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	protein	(mg/ml)
2	1	drop		0.02 (%)
3	1	reservoir	DMSO	4-6 (%)