2KWG

Solution structure of a fully modified 2'-F/2'-OMe siRNA construct

Spectrometer

Experimental method: SOLUTION NMR

Spectrometer ID	Spectrometer maker	Spectrometer model	Spectrometer type	Spectrometer field strength
1	Varian	Uniform NMR System	Varian Uniform NMR System	800
2	Varian	Uniform NMR System	Varian Uniform NMR System	600

Experiment

experiment id	conditions id	solution id	Experiment type
1	1	1	2D DQF-COSY
2	1	1	2D 1H-1H NOESY
3	1	2	2D 1H-1H NOESY
4	2	1	2D 1H-1H NOESY
5	2	2	2D 1H-1H NOESY
6	1	1	2D HP-COSY
7	1	1	2D 1H-1H NOESY

NMR Sample

conditions id	NMR sample pH	NMR sample pressure	NMR sample temperature
1	6.8	ambient	25
2	6.8	ambient	5

Conformers

Conformers Calculated Total Number	100
Conformers Submitted Total Number	10