2BXU
Design and Discovery of Novel, Potent Thrombin Inhibitors with a Solubilizing Cationic P1-P2-Linker
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | SLS BEAMLINE X06SA |
Synchrotron site | SLS |
Beamline | X06SA |
Temperature [K] | 100 |
Spacegroup name | C 1 2 1 |
Unit cell lengths | 70.505, 71.917, 72.522 |
Unit cell angles | 90.00, 100.35, 90.00 |
Refinement procedure
Resolution | 20.000 - 2.800 |
Rwork | 0.235 |
Structure solution method | OTHER |
RMSD bond length | 0.005 |
RMSD bond angle | 1.130 |
Refinement software | CNX (2002) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 20.000 |
High resolution limit [Å] | 2.800 |
Rmerge | 0.050 |
Number of reflections | 8499 |
Completeness [%] | 97.0 |
Redundancy | 2.5 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |