2XVD
ephB4 kinase domain inhibitor complex
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU MICROMAX-007 |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2006-09-13 |
| Detector | RIGAKU CCD |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 46.708, 53.315, 61.330 |
| Unit cell angles | 90.00, 111.75, 90.00 |
Refinement procedure
| Resolution | 43.050 - 1.700 |
| R-factor | 0.17687 |
| Rwork | 0.175 |
| R-free | 0.20913 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 2vwu |
| RMSD bond length | 0.015 |
| RMSD bond angle | 1.436 |
| Data reduction software | d*TREK |
| Data scaling software | d*TREK |
| Phasing software | AMoRE |
| Refinement software | REFMAC (5.5.0109) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 43.000 | 1.760 |
| High resolution limit [Å] | 1.700 | 1.700 |
| Rmerge | 0.050 | 0.360 |
| Number of reflections | 28154 | |
| <I/σ(I)> | 14.3 | 2 |
| Completeness [%] | 90.9 | 46.9 |
| Redundancy | 3.32 | 2.06 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 7.5 | PH 7.5 |
