2WK3
Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-42)
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 19-ID |
| Synchrotron site | APS |
| Beamline | 19-ID |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2008-02-21 |
| Detector | ADSC CCD |
| Spacegroup name | P 65 |
| Unit cell lengths | 261.628, 261.628, 90.675 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 49.440 - 2.590 |
| R-factor | 0.189 |
| Rwork | 0.187 |
| R-free | 0.23200 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.022 |
| RMSD bond angle | 1.959 |
| Refinement software | REFMAC (5.5.0088) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 50.000 |
| High resolution limit [Å] | 2.600 |
| Rmerge | 0.090 |
| Number of reflections | 104637 |
| <I/σ(I)> | 17.6 |
| Completeness [%] | 99.0 |
| Redundancy | 3.6 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
