2W3L

Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU MICROMAX-007 HF
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	2006-03-13
Detector	RIGAKU (RAXIS4)
Spacegroup name	P 21 21 21
Unit cell lengths	68.000, 68.320, 70.670
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	20.000 - 2.100
R-factor	0.218
Rwork	0.218
R-free	0.25800
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.018
RMSD bond angle	1.718
Refinement software	REFMAC (5.2.0019)

Data quality characteristics

	Overall
Low resolution limit [Å]	19.910
High resolution limit [Å]	2.100
Rmerge	0.100
Number of reflections	22774
<I/σ(I)>	8.4
Completeness [%]	99.8
Redundancy	6.97

Crystallization Conditions

crystal ID	method	pH	temperature	details
1