22RD
High-resolution cryo-EM structure of human Polo-like kinase 1 in complex with onvansertib
EM specimen
| Vitrification | Yes |
EM Data Collection
| Microscope | TFS KRIOS |
| Electron Gun | FIELD EMISSION GUN |
| Accelerating Voltage (kV) | 300 |
| Detector | FEI FALCON IV (4k x 4k) |
3D Reconstruction
| Method | SINGLE PARTICLE |
| Resolution (Å) | 3.38 |
| Number of Particle | 6021153 |
| Software | cryoSPARC,Coot,PHENIX |
| CTF correction | PHASE FLIPPING ONLY |
