1PXN

HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-[4-(4-Methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.5 Å)

Cell axes52.89671.70970.002
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits24.82 - 2.50
the highest resolution shell value2.660 - 2.500
R-factor0.23
R-work0.23000
the highest resolution shell value0.251
R-free0.27700
the highest resolution shell value0.379
RMSD bond length0.010
RMSD bond angle1.500

Data Collection Statistics

Resolution limits25.00 - 2.50
the highest resolution shell value -
Number of reflections9345
Rmerge_l_obs0.089
the highest resolution shell value0.490
Completeness96.4
Redundancy11

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, HANGING DROP7.8277

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*