1HVR

RATIONAL DESIGN OF POTENT, BIOAVAILABLE, NONPEPTIDE CYCLIC UREAS AS HIV PROTEASE INHIBITORS

Experimental procedure

Spacegroup name	P 61
Unit cell lengths	62.800, 62.800, 83.500
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	? - 1.800
R-factor	0.193
Rwork	0.193
RMSD bond length	0.016
RMSD bond angle	3.300
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	1.800 *
Rmerge	0.061 *
Total number of observations	55263 *
Number of reflections	15417 *
Completeness [%]	94.0 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	unknown *	5.4 *