1YWN
Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 17-ID |
| Synchrotron site | APS |
| Beamline | 17-ID |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2001-05-01 |
| Detector | MARRESEARCH |
| Wavelength(s) | 1.0 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 37.953, 95.595, 95.803 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 47.890 - 1.710 |
| R-factor | 0.20564 |
| Rwork | 0.205 |
| R-free | 0.23005 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1y6a |
| RMSD bond length | 0.012 |
| RMSD bond angle | 1.485 |
| Data scaling software | SCALEPACK |
| Phasing software | AMoRE |
| Refinement software | REFMAC (5.2.0005) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 50.000 | 1.760 |
| High resolution limit [Å] | 1.700 | 1.700 |
| Rmerge | 0.047 | 0.383 |
| Number of reflections | 37357 | |
| <I/σ(I)> | 31.38 | 2.63 |
| Completeness [%] | 94.7 | 71.8 |
| Redundancy | 6.43 | 4.3 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | VAPOR DIFFUSION, HANGING DROP |
