1YVF

Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	CCD
Collection date	2002-03-07
Detector	ADSC QUANTUM 210
Wavelength(s)	1.000
Spacegroup name	P 32 2 1
Unit cell lengths	90.879, 90.879, 188.516
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	30.000 - 2.500
R-factor	0.24
Rwork	0.240
R-free	0.30300
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	DENZO
Data scaling software	SCALEPACK
Refinement software	CNS

Data quality characteristics

	Overall	Inner shell	Outer shell
Low resolution limit [Å]	50.000	50.000	2.590
High resolution limit [Å]	2.500	5.380	2.500
Rmerge	0.076	0.042	0.383
Number of reflections	31629
Completeness [%]	98.3	92.4	99.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1