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CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH (3A-ALPHA-,4-ALPHA 7-ALPHA-,7A-ALPHA-)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	CCD
Collection date	2000-03-25
Detector	MARRESEARCH
Wavelength(s)	1.00
Spacegroup name	P 21 21 21
Unit cell lengths	54.870, 65.940, 70.460
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	19.600 - 2.200
Rwork	0.249
R-free	0.30100
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	1i38
RMSD bond length	0.012
RMSD bond angle	1.200
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	AMoRE
Refinement software	CNX (2000.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	20.000	2.280
High resolution limit [Å]	2.200	2.200
Rmerge	0.055	0.372
Number of reflections	13386
<I/σ(I)>	18.2	1.9
Completeness [%]	99.7	100
Redundancy	4	4

Crystallization Conditions

crystal ID	method	pH	temperature	details
1