1WAQ
Crystal structure of human Growth and Differentiation Factor 5 (GDF-5)
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2002-08-16 |
| Detector | MARRESEARCH |
| Spacegroup name | P 32 2 1 |
| Unit cell lengths | 97.771, 97.771, 43.325 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 17.000 - 2.280 |
| R-factor | 0.223 |
| Rwork | 0.222 |
| R-free | 0.23700 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 1bmp |
| RMSD bond length | 0.017 |
| RMSD bond angle | 1.412 |
| Data reduction software | MOSFLM |
| Data scaling software | SCALA |
| Phasing software | CNS |
| Refinement software | REFMAC (5.1.24) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 84.520 | 2.390 |
| High resolution limit [Å] | 2.280 | 2.280 |
| Rmerge | 0.050 | 0.190 |
| Number of reflections | 11084 | |
| <I/σ(I)> | 8.7 | 3.4 |
| Completeness [%] | 98.3 | 93.3 |
| Redundancy | 4.5 | 2.7 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 25% 2-METHLY-2,4-PENTANEDIOL, 0.1M SODIUM CITRATE PH 4.0 |
