1OEC

FGFr2 kinase domain

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SRS BEAMLINE PX9.6
Synchrotron site	SRS
Beamline	PX9.6
Temperature [K]	287
Detector technology	CCD
Detector	ADSC CCD
Spacegroup name	I 2 2 2
Unit cell lengths	69.760, 80.500, 120.170
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	100.000 - 2.400
R-factor	0.211
Rwork	0.211
R-free	0.28500
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	1gjo
RMSD bond length	0.007
RMSD bond angle	1.240
Data reduction software	DENZO
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	X-PLOR (3.851)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	40.000	2.450
High resolution limit [Å]	2.400	2.400
Rmerge	0.046	0.199
Number of reflections	87022
<I/σ(I)>	22.1
Completeness [%]	98.0	78.9
Redundancy	6.4

Crystallization Conditions

crystal ID	method	pH	temperature	details
1		5.9		pH 5.90