1N95

Aryl Tetrahydrophyridine Inhbitors of Farnesyltranferase: Glycine, Phenylalanine and Histidine Derivatives

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	CCD
Collection date	2001-04-04
Detector	MARRESEARCH
Wavelength(s)	1.000
Spacegroup name	P 61
Unit cell lengths	171.126, 171.126, 69.404
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	43.590 - 2.300
Rwork	0.337
R-free	0.35800
Structure solution method	FOURIER SYNTHESIS
RMSD bond length	0.014
RMSD bond angle	1.800 *
Data reduction software	HKL-2000
Data scaling software	SCALEPACK
Phasing software	X-PLOR
Refinement software	X-PLOR (3.1)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	43.590	2.400
High resolution limit [Å]	2.300	2.300
Number of reflections	43175
Completeness [%]	83.4	64

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	unknown *