1CPI
REGIOSELECTIVE STRUCTURAL AND FUNCTIONAL MIMICRY OF PEPTIDES. DESIGN OF HYDROLYTICALLY STABLE CYCLIC PEPTIDOMIMETIC INHIBITORS OF HIV-1 PROTEASE
Experimental procedure
| Temperature [K] | 289 |
| Detector technology | IMAGE PLATE |
| Collection date | 1993-12-10 |
| Detector | RIGAKU |
| Wavelength(s) | 1.5418 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 51.300, 58.800, 62.300 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 8.000 - 2.050 |
| R-factor | 0.163 |
| Rwork | 0.163 |
| R-free | 0.23700 |
| RMSD bond length | 0.009 |
| RMSD bond angle | 26.900 * |
| Data reduction software | PROCESS ((HIGASHI/RIGAKU)) |
| Phasing software | X-PLOR (3.1) |
| Refinement software | X-PLOR (3.1) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 51.000 |
| High resolution limit [Å] | 2.050 |
| Rmerge | 0.071 |
| Number of reflections | 11539 |
| Completeness [%] | 94.0 |
| Redundancy | 3 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | Vapor diffusion, hanging drop * | 5.5 | 20 * | pH 5.5 |
Crystallization Reagents in Literatures
| ID | crystal ID | solution | reagent name | concentration (unit) | details |
| 1 | 1 | reservoir | ammonium sulfate | 40 (%) | |
| 2 | 1 | reservoir | acetate |
