12AP
Cryo-EM structure of alpha-synuclein filaments (singlet) from Parkinson's disease with A53T mutation in SNCA
EM specimen
| Vitrification | Yes |
EM Data Collection
| Microscope | TFS KRIOS |
| Electron Gun | FIELD EMISSION GUN |
| Accelerating Voltage (kV) | 300 |
| Detector | TFS FALCON 4i (4k x 4k) |
3D Reconstruction
| Method | HELICAL |
| Resolution (Å) | 2.1 |
| Software | RELION,Servalcat,REFMAC |
| CTF correction | PHASE FLIPPING ONLY |
