8UXC
 
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8UXE
 | | Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 | | Descriptor: | 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | | Authors: | Miotto, M.C, Marks, A.R. | | Deposit date: | 2023-11-09 | | Release date: | 2023-11-22 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
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8UXF
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8UXG
 | | Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210 | | Descriptor: | 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | | Authors: | Miotto, M.C, Marks, A.R. | | Deposit date: | 2023-11-09 | | Release date: | 2023-11-22 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
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8UXH
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8UXI
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8UXL
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8UXM
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8UZT
 | | Mitochondrial single-stranded binding protein bound to DNA | | Descriptor: | GLYCEROL, SODIUM ION, Single-stranded DNA-binding protein, ... | | Authors: | Riccio, A.A, Pedersen, L.C, Bouvette, J, Borgnia, J.M, Copeland, W.C. | | Deposit date: | 2023-11-16 | | Release date: | 2024-08-21 | | Last modified: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase gamma.
Nucleic Acids Res., 52, 2024
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8V8K
 | | Crystal Structure of Nanobody NbE | | Descriptor: | Nanobody NbE | | Authors: | Koehl, A, Manglik, A, Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Steyaert, J, Ballet, S, Boland, A, Stoeber, M. | | Deposit date: | 2023-12-05 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist
To Be Published
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8VD6
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8VPG
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8VPH
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8VPI
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8VS6
 | | L-TGF-b3/avb8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Jin, M, Cheng, Y, Nishimura, S.L. | | Deposit date: | 2024-01-23 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 2024
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8VSB
 | | L-TGF-b3/GARP | | Descriptor: | Transforming growth factor beta activator LRRC32, Transforming growth factor beta-3 proprotein | | Authors: | Jin, M, Cheng, Y, Nishimura, S.L. | | Deposit date: | 2024-01-23 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 2024
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8VSC
 | | L-TGF-b1/GARP | | Descriptor: | Transforming growth factor beta activator LRRC32, Transforming growth factor beta-1 proprotein | | Authors: | Jin, M, Cheng, Y, Nishimura, S.L. | | Deposit date: | 2024-01-23 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 2024
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8VSD
 | | avb8/L-TGF-b1/GARP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Jin, M, Cheng, Y, Nishimura, S.L. | | Deposit date: | 2024-01-23 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Cell, 2024
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8VT9
 | | WT SthK in the presence of PIP2 and cAMP | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Transcriptional regulator, ... | | Authors: | Schmidpeter, P.A.M, Thon, O, Nimigean, C.M. | | Deposit date: | 2024-01-26 | | Release date: | 2024-09-25 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.
Nat Commun, 15, 2024
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8VTA
 | | SthK R120A in the presence of PIP2 and cAMP | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Transcriptional regulator, ... | | Authors: | Schmidpeter, P.A.M, Thon, O, Nimigean, C.M. | | Deposit date: | 2024-01-26 | | Release date: | 2024-09-25 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.
Nat Commun, 15, 2024
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8VTB
 | | SthK R120A R124A in the presence of PIP2 and cAMP | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Transcriptional regulator, ... | | Authors: | Schmidpeter, P.A.M, Thon, O, Nimigean, C.M. | | Deposit date: | 2024-01-26 | | Release date: | 2024-09-25 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.
Nat Commun, 15, 2024
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8W6K
 | | in situ room temperature Laue crystallography | | Descriptor: | Lysozyme C | | Authors: | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | | Deposit date: | 2023-08-29 | | Release date: | 2024-01-17 | | Last modified: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | BL03HB: a Laue microdiffraction beamline for both protein crystallography and materials science at SSRF
Nucl.Sci.Tech., 35, 2024
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8WHN
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8WKO
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8WKR
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