7FY6
 
 | Crystal Structure of human FABP4 in complex with 6-phenyl-11H-pyrimido[4,5-c][2]benzazepin-3-amine, i.e. SMILES C1(=Nc2c(Cc3c1cccc3)cnc(n2)N)c1ccccc1 with IC50=1.4 microM | Descriptor: | 10-phenyl-5H-pyrimido[4,5-c][2]benzazepin-2-amine, FORMIC ACID, Fatty acid-binding protein, ... | Authors: | Ehler, A, Benz, J, Obst, U, Fryer, R, Rudolph, M.G. | Deposit date: | 2023-04-27 | Release date: | 2023-06-14 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Crystal Structure of a human FABP4 complex To be published
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7FYI
 
 | Crystal Structure of human FABP4 in complex with 5-[(4-chlorophenyl)sulfanylmethyl]-2-methylpyrazol-3-ol, i.e. SMILES C1(=CC(=NN1C)CSc1ccc(cc1)Cl)O with IC50=17 microM | Descriptor: | 3-{[(4-chlorophenyl)sulfanyl]methyl}-1-methyl-1H-pyrazol-5-ol, Fatty acid-binding protein, adipocyte, ... | Authors: | Ehler, A, Benz, J, Obst, U, Kumagai, Y, Rudolph, M.G. | Deposit date: | 2023-04-27 | Release date: | 2023-06-14 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Crystal Structure of a human FABP4 complex To be published
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7FYL
 
 | Crystal Structure of human FABP4 in complex with 6-(4-chlorophenyl)sulfanyl-2-(4-methylphenyl)sulfanylhexanoic acid, i.e. SMILES c1(S[C@@H](CCCCSc2ccc(cc2)Cl)C(=O)O)ccc(cc1)C with IC50=0.25724 microM | Descriptor: | (2R)-6-[(4-chlorophenyl)sulfanyl]-2-[(4-methylphenyl)sulfanyl]hexanoic acid, (2S)-6-[(4-chlorophenyl)sulfanyl]-2-[(4-methylphenyl)sulfanyl]hexanoic acid, Fatty acid-binding protein, ... | Authors: | Ehler, A, Benz, J, Obst, U, Boehringer, M, Rudolph, M.G. | Deposit date: | 2023-04-27 | Release date: | 2023-06-14 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Crystal Structure of a human FABP4 complex To be published
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7FYU
 
 | Crystal Structure of human FABP4 in complex with 2-benzyl-6-tert-butyl-3-methyl-4-phenyl-5-(1H-tetrazol-5-yl)pyridine, i.e. SMILES N1C(=NN=N1)c1c(nc(c(c1c1ccccc1)C)Cc1ccccc1)C(C)(C)C with IC50=0.176219 microM | Descriptor: | (5M)-2-benzyl-6-tert-butyl-3-methyl-4-phenyl-5-(1H-tetrazol-5-yl)pyridine, Fatty acid-binding protein, adipocyte, ... | Authors: | Ehler, A, Benz, J, Obst, U, Buettelmann, B, Rudolph, M.G. | Deposit date: | 2023-04-27 | Release date: | 2023-06-14 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Crystal Structure of a human FABP4 complex To be published
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7FYX
 
 | Crystal Structure of human FABP4 in complex with 2-[(3-phenylthiophen-2-yl)carbamoyl]cyclopentene-1-carboxylic acid, i.e. SMILES S1C(=C(C=C1)c1ccccc1)NC(=O)C1=C(CCC1)C(=O)O with IC50=0.201 microM | Descriptor: | 2-[(3-phenylthiophen-2-yl)carbamoyl]cyclopent-1-ene-1-carboxylic acid, Fatty acid-binding protein, adipocyte, ... | Authors: | Ehler, A, Benz, J, Obst, U, Ceccarelli-Simona, M, Rudolph, M.G. | Deposit date: | 2023-04-27 | Release date: | 2023-06-14 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of a human FABP4 complex To be published
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7FZF
 
 | Crystal Structure of human FABP4 in complex with 2-(6-methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-3-yl)butanoic acid, i.e. SMILES C12=C(N=CN(C1=O)[C@@H](C(=O)O)CC)SC(=C2c1ccccc1)C with IC50=7.52669 microM | Descriptor: | (2R)-2-(6-methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-3(4H)-yl)butanoic acid, (2S)-2-(6-methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-3(4H)-yl)butanoic acid, Fatty acid-binding protein, ... | Authors: | Ehler, A, Benz, J, Obst, U, Brunner, M, Rudolph, M.G. | Deposit date: | 2023-04-27 | Release date: | 2023-06-14 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Crystal Structure of a human FABP4 complex To be published
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7NRJ
 
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7O5N
 
 | OXA-48 with decarbamylated Lys73 in complex with avibactam at pH 8.0 | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1-BUTANOL, Beta-lactamase, ... | Authors: | Zhou, Q, Zhang, Z, He, Y, Jin, Y. | Deposit date: | 2021-04-09 | Release date: | 2022-04-20 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7O5T
 
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7O9N
 
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7PEH
 
 | Apo OXA-48 with fully carbamylated Lys73 at pH 7.5 | Descriptor: | 1-BUTANOL, Beta-lactamase | Authors: | Zhou, Q, He, Y, Jin, Y. | Deposit date: | 2021-08-10 | Release date: | 2022-08-24 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7PEI
 
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7PFN
 
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7PGO
 
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7PSE
 
 | Acetyllysine73-incorporated OXA-48 complexed with oxacillin | Descriptor: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, 1-BUTANOL, Beta-lactamase, ... | Authors: | Zhou, Q, He, Y, Jin, Y. | Deposit date: | 2021-09-23 | Release date: | 2022-10-05 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7Q14
 
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7QPL
 
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7T0L
 
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7X7W
 
 | The X-ray Crystallographic Structure of D-Psicose 3-epimerase from Clostridia bacterium | Descriptor: | D-PSICOSE 3-EPIMERASE, MANGANESE (II) ION | Authors: | Li, Z.F, Ban, X.F, Xie, X.F, Tian, Y.X, Li, C.M, Gu, Z.B. | Deposit date: | 2022-03-10 | Release date: | 2022-09-07 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of a novel homodimeric D-allulose 3-epimerase from a Clostridia bacterium. Acta Crystallogr D Struct Biol, 78, 2022
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8BWV
 
 | Crystal Structure of SilF Cu(I) | Descriptor: | COPPER (II) ION, SilF | Authors: | Lithgo, R.M, Carr, S.B, Scott, D.J, Quigley, A. | Deposit date: | 2022-12-07 | Release date: | 2024-01-24 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF. J.Biol.Chem., 299, 2023
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8IOZ
 
 | Crystal structure of transaminase | Descriptor: | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase | Authors: | Li, Q, Zhu, Y.M, Gao, J, Wei, H.L, Han, X, Liu, W.D, Sun, Y.X. | Deposit date: | 2023-03-13 | Release date: | 2024-01-24 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Protein engineering of transaminase facilitating enzyme cascade reaction for the biosynthesis of azasugars. Iscience, 27, 2024
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8ISC
 
 | Crystal structure of MV in complex with LLP | Descriptor: | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase | Authors: | Li, Q, Zhu, Y.M, Gao, J, Wei, H.L, Han, X, Liu, W.D, Sun, Y.X. | Deposit date: | 2023-03-20 | Release date: | 2024-01-24 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Protein engineering of transaminase facilitating enzyme cascade reaction for the biosynthesis of azasugars. Iscience, 27, 2024
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8IVP
 
 | Crystal structure of MV in complex with LLP and FRU from Mycobacterium vanbaalenii | Descriptor: | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase, D-fructose | Authors: | Li, Q, Zhu, Y.M, Gao, J, Wei, H.L, Han, X, Liu, W.D, Sun, Y.X. | Deposit date: | 2023-03-28 | Release date: | 2024-01-24 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Protein engineering of transaminase facilitating enzyme cascade reaction for the biosynthesis of azasugars. Iscience, 27, 2024
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8K48
 
 | LTD of arabidopsis thaliana | Descriptor: | Protein LHCP TRANSLOCATION DEFECT | Authors: | Wang, C, Xu, X.M. | Deposit date: | 2023-07-17 | Release date: | 2024-07-24 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | LTD coordinates chlorophyll biosynthesis and LIGHT-HARVESTING CHLOROPHYLL A/B-BINDING PROTEIN transport. Plant Cell, 37, 2025
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8KAO
 
 | Glutamate dehydrogenase-69O | Descriptor: | 2-oxopentanoic acid, Glutamate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Sakuraba, H, Ohshima, T. | Deposit date: | 2023-08-03 | Release date: | 2024-08-07 | Last modified: | 2025-08-06 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural insight into the unique substrate specificity of glutamate dehydrogenase from Saccharolobus solfataricus. Extremophiles, 29, 2025
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