9CV6
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9EP8
| Crystal structure of ROCK2 in complex with a 8-(azaindolyl)-benzoazepinone inhibitor | 分子名称: | 1,2-ETHANEDIOL, 8-(azaindolyl)-benzoazepinone, Rho-associated protein kinase 2 | 著者 | Pala, D, Clark, D, Pioselli, B, Accetta, A, Rancati, F. | 登録日 | 2024-03-18 | 公開日 | 2024-09-25 | 最終更新日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors. Rsc Med Chem, 2024
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9F1B
| Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Yudin, D, Scaiola, A, Ban, N. | 登録日 | 2024-04-18 | 公開日 | 2024-08-21 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
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9F1C
| Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Yudin, D, Scaiola, A, Ban, N. | 登録日 | 2024-04-18 | 公開日 | 2024-08-21 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
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9F1D
| Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Yudin, D, Scaiola, A, Ban, N. | 登録日 | 2024-04-18 | 公開日 | 2024-08-21 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
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9F5S
| EVA71 E096A native particle | 分子名称: | SPHINGOSINE, VP0, VP1, ... | 著者 | Kingston, N.J, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M, Filman, D.J, Snowden, J.S.S. | 登録日 | 2024-04-30 | 公開日 | 2024-09-04 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate. Plos Pathog., 20, 2024
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9F6A
| EVA71 E096A native particle | 分子名称: | SPHINGOSINE, VP0, VP1, ... | 著者 | Kingston, N.J, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M, Filman, D.J, Snowden, J.S.S. | 登録日 | 2024-04-30 | 公開日 | 2024-09-04 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate. Plos Pathog., 20, 2024
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9FEK
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9FFB
| ss-dsDNA-FANCD2-FANCI complex | 分子名称: | DNA (5'-D(P*CP*GP*AP*TP*GP*TP*CP*TP*CP*TP*AP*GP*AP*CP*AP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*CP*TP*GP*TP*CP*TP*AP*GP*AP*GP*AP*CP*AP*TP*CP*GP*AP*T)-3'), Fanconi anemia complementation group I, ... | 著者 | Alcon, P, Passmore, L.A. | 登録日 | 2024-05-22 | 公開日 | 2024-07-31 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions. Nature, 632, 2024
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9FFF
| dsDNA-FANCD2-FANCI complex | 分子名称: | DNA (32-MER), DNA (33-MER), Fanconi anemia complementation group I, ... | 著者 | Alcon, P, Passmore, L.A. | 登録日 | 2024-05-23 | 公開日 | 2024-07-31 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions. Nature, 632, 2024
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9FJ3
| Structure of ubiquitin bound of coiled-coil UIM form 2 | 分子名称: | 3-[1-(2-oxidanylideneethyl)-1,2,3-triazol-4-yl]propanal, GLU-GLN-GLU-ILE-GLU-GLU-LEU-GLU-ILE-GLU-ILE-ALA-ILE-LEU-LEU-SER-GLU-ILE-GLU-GLY, LYS-GLN-LYS-ILE-ALA-ALA-LEU-LYS-TYR-LYS-ILE-ALA-ALA-LEU-LYS-GLN-LYS-ILE, ... | 著者 | Paredes Vergara, P, Huang, D.T. | 登録日 | 2024-05-30 | 公開日 | 2024-09-18 | 最終更新日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | An engineered ubiquitin binding coiled coil peptide. Chem Sci, 2024
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9FJ4
| Structure of ubiquitin bound to coiled coil-UIM form 1 | 分子名称: | 3-[1-(2-oxidanylideneethyl)-1,2,3-triazol-4-yl]propanal, GLU-GLN-GLU-ILE-GLU-GLU-LEU-GLU-ILE-GLU-ILE-ALA-ILE-LEU-LEU-SER-GLU-ILE-GLU-GLY, LYS-GLN-LYS-ILE-ALA-ALA-LEU-LYS-TYR-LYS-ILE-ALA-ALA-LEU-LYS-GLN-LYS-ILE-GLN, ... | 著者 | Paredes Vergara, P, Huang, D.T. | 登録日 | 2024-05-30 | 公開日 | 2024-09-18 | 最終更新日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | An engineered ubiquitin binding coiled coil peptide. Chem Sci, 2024
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9FJM
| Cryo-EM structure of the phalloidin-bound pointed end of the actin filament. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | 登録日 | 2024-05-31 | 公開日 | 2024-09-11 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly. Nat Commun, 15, 2024
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9FJO
| Structure of the undecorated pointed end of F-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | 登録日 | 2024-05-31 | 公開日 | 2024-09-11 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly. Nat Commun, 15, 2024
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9FJU
| Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | 登録日 | 2024-05-31 | 公開日 | 2024-09-11 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly. Nat Commun, 15, 2024
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9FJY
| Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | 登録日 | 2024-05-31 | 公開日 | 2024-09-11 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly. Nat Commun, 15, 2024
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9FPZ
| Human NatA-MAP2 80S ribosome complex | 分子名称: | 28S rRNA, 5.8S rRNA (58-MER), 60S ribosomal protein L19, ... | 著者 | Klein, M.A, Wild, K, Sinning, I. | 登録日 | 2024-06-14 | 公開日 | 2024-07-03 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome. Nat Commun, 15, 2024
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9FQ0
| Human NatA-NAC-MAP1 80S ribosome complex | 分子名称: | 28S rRNA, 5.8S rRNA, 60S ribosomal protein L19, ... | 著者 | Klein, M.A, Wild, K, Sinning, I. | 登録日 | 2024-06-14 | 公開日 | 2024-07-03 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (4.67 Å) | 主引用文献 | Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome. Nat Commun, 15, 2024
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9FS9
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9FSA
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9GBE
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9GD0
| Structure of a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp. | 分子名称: | DNA (250-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | 登録日 | 2024-08-04 | 公開日 | 2024-09-18 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
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9GD1
| Structure of Chd1 bound to a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | 著者 | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | 登録日 | 2024-08-04 | 公開日 | 2024-09-18 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
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9GD2
| Structure of Chd1 bound to a dinucleosome with a dyad-to-dyad distance of 103 bp. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | 著者 | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | 登録日 | 2024-08-04 | 公開日 | 2024-09-18 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
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9GD3
| Structure of a mononucleosome bound by one copy of Chd1 with the DBD on the exit-side DNA. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | 著者 | Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. | 登録日 | 2024-08-04 | 公開日 | 2024-09-18 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
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