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Updated PDB entries
5DKP
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BU of 5dkp by Molmil
Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.
Descriptor: ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION, SODIUM ION, ...
Authors:Goodreid, J.D, Janetzko, J, Santa Maria Jr, J.P, Wong, K, Leung, E, Eger, B.T, Bryson, S, Pai, E.F, Gray-Owen, S.D, Walker, S, Houry, W.A, Batey, R.A.
Deposit date:2015-09-03
Release date:2016-01-27
Last modified:2025-07-09
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity.
J.Med.Chem., 59, 2016
5HTB
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BU of 5htb by Molmil
Crystal structure of haspin (GSG2) in complex with bisubstrate inhibitor ARC-3353.
Descriptor: (2R,3S,4R,5R,6R)-6-((1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYLOXY)-5-AMINO-2-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-3,4-DIOL, (3R)-4-amino-3-{[6-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]carbonyl}amino)hexanoyl]amino}-4-oxobutanoic acid (non-preferred name), (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Chaikuad, A, Heroven, C, Lavogina, D, Kestav, K, Uri, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2016-01-26
Release date:2016-05-11
Last modified:2025-07-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors.
Acta Crystallogr.,Sect.F, 72, 2016
5M32
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BU of 5m32 by Molmil
Human 26S proteasome in complex with Oprozomib
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H.
Deposit date:2016-10-14
Release date:2017-07-05
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.
Nat Commun, 8, 2017
5MC6
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BU of 5mc6 by Molmil
Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R.
Deposit date:2016-11-09
Release date:2017-01-18
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
5MKE
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BU of 5mke by Molmil
cryoEM Structure of Polycystin-2 in complex with cations and lipids
Descriptor: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wilkes, M, Madej, M.G, Ziegler, C.
Deposit date:2016-12-04
Release date:2017-01-18
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.
Nat. Struct. Mol. Biol., 24, 2017
5MM4
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BU of 5mm4 by Molmil
Ustilago maydis kinesin-5 motor domain in the AMPPNP state bound to microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Moores, C.A, von Loeffelholz, O.
Deposit date:2016-12-08
Release date:2018-06-27
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules.
J.Struct.Biol., 2019
5MQF
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BU of 5mqf by Molmil
Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ...
Authors:Bertram, K, Hartmuth, K, Kastner, B.
Deposit date:2016-12-20
Release date:2017-03-22
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
5MZ6
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BU of 5mz6 by Molmil
Cryo-EM structure of a Separase-Securin complex from Caenorhabditis elegans at 3.8 A resolution
Descriptor: Interactor of FizzY protein, SEParase
Authors:Boland, A, Martin, T.G, Zhang, Z, Yang, J, Bai, X.C, Chang, L, Scheres, S.H.W, Barford, D.
Deposit date:2017-01-31
Release date:2017-03-08
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
5NSR
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BU of 5nsr by Molmil
Cryo-EM structure of RNA polymerase-sigma54 holo enzyme with promoter DNA closed complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Glyde, R, Ye, F.Z, Darbari, V.C, Zhang, N, Buck, M, Zhang, X.D.
Deposit date:2017-04-26
Release date:2017-06-28
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation.
Mol. Cell, 67, 2017
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
Authors:Bertram, K, Kastner, B.
Deposit date:2017-06-20
Release date:2017-08-16
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
5OOM
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BU of 5oom by Molmil
Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA
Descriptor: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V.
Deposit date:2017-08-08
Release date:2017-09-13
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
6ESF
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BU of 6esf by Molmil
Nucleosome : Class 1
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
6ESG
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BU of 6esg by Molmil
Nucleosome breathing : Class 2
Descriptor: DNA (141-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
6ESH
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BU of 6esh by Molmil
Nucleosome breathing : Class 3
Descriptor: DNA (137-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
6EVW
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BU of 6evw by Molmil
Cryo-EM structure of GMPCPP-microtubule co-polymerised with doublecortin
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Manka, S.W.
Deposit date:2017-11-02
Release date:2018-07-04
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6EXN
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BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
Authors:Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
Deposit date:2017-11-08
Release date:2018-01-17
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
6EZ8
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BU of 6ez8 by Molmil
Human Huntingtin-HAP40 complex structure
Descriptor: Factor VIII intron 22 protein, Huntingtin
Authors:Guo, Q, Bin, H, Cheng, J, Pfeifer, G, Baumeister, W, Fernandez-Busnadiego, R, Kochanek, S.
Deposit date:2017-11-14
Release date:2018-02-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The cryo-electron microscopy structure of huntingtin.
Nature, 555, 2018
6F2D
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BU of 6f2d by Molmil
A FliPQR complex forms the core of the Salmonella type III secretion system export apparatus.
Descriptor: Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR
Authors:Johnson, S, Kuhlen, L, Abrusci, P, Lea, S.M.
Deposit date:2017-11-24
Release date:2018-07-04
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the core of the type III secretion system export apparatus.
Nat. Struct. Mol. Biol., 25, 2018
6F36
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BU of 6f36 by Molmil
Polytomella Fo model
Descriptor: Mitochondrial ATP synthase subunit 6, Mitochondrial ATP synthase subunit ASA6, Mitochondrial ATP synthase subunit c
Authors:Yildiz, O, Kuehlbrandt, W, Klusch, N, Murphy, B.J, Mills, D.J.
Deposit date:2017-11-28
Release date:2017-12-20
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of proton translocation and force generation in mitochondrial ATP synthase.
Elife, 6, 2017
6F95
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BU of 6f95 by Molmil
AlfA from B. subtilis plasmid pLS32 filament structure at 3.4 A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AlfA, MAGNESIUM ION
Authors:Szewczak-Harris, A, Lowe, J.
Deposit date:2017-12-14
Release date:2018-04-11
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Cryo-EM reconstruction of AlfA fromBacillus subtilisreveals the structure of a simplified actin-like filament at 3.4- angstrom resolution.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FEQ
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BU of 6feq by Molmil
Structure of inhibitor-bound ABCG2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ...
Authors:Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P.
Deposit date:2018-01-03
Release date:2018-04-11
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat. Struct. Mol. Biol., 25, 2018
6FIK
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BU of 6fik by Molmil
ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS
Descriptor: Polyketide synthase
Authors:Herbst, D.A, Huitt-Roehl, C.R, Jakob, R.P, Townsend, C.A, Maier, T.
Deposit date:2018-01-18
Release date:2018-03-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:The structural organization of substrate loading in iterative polyketide synthases.
Nat. Chem. Biol., 14, 2018
6FLP
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BU of 6flp by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex without RNA hairpin bound to NusA
Descriptor: DNA (30-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Guo, X, Weixlbaumer, A.
Deposit date:2018-01-26
Release date:2018-03-07
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
6FLQ
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BU of 6flq by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA
Descriptor: DNA (31-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Guo, X, Weixlbaumer, A.
Deposit date:2018-01-26
Release date:2018-03-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
6FN1
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BU of 6fn1 by Molmil
Zosuquidar and UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Human-mouse chimeric ABCB1 (ABCBHM), UIC2 Antigen Binding Fragment Heavy Chain, ...
Authors:Alam, A, Locher, K.P.
Deposit date:2018-02-02
Release date:2018-02-21
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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