1R46
 
 | | Structure of human alpha-galactosidase | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Garman, S.C, Garboczi, D.N. | | 登録日 | 2003-10-03 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
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1R47
 | | Structure of human alpha-galactosidase | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | | 著者 | Garman, S.C, Garboczi, D.N. | | 登録日 | 2003-10-03 | | 公開日 | 2004-03-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
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1R49
 | | Human topoisomerase I (Topo70) double mutant K532R/Y723F | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I | | 著者 | Interthal, H, Quigley, P.M, Hol, W.G, Champoux, J.J. | | 登録日 | 2003-10-03 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | The role of lysine 532 in the catalytic mechanism of human topoisomerase I.
J.Biol.Chem., 279, 2004
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1R4A
 | | Crystal Structure of GTP-bound ADP-ribosylation Factor Like Protein 1 (Arl1) and GRIP Domain of Golgin245 COMPLEX | | 分子名称: | ADP-ribosylation factor-like protein 1, Golgi autoantigen, golgin subfamily A member 4, ... | | 著者 | Wu, M, Lu, L, Hong, W, Song, H. | | 登録日 | 2003-10-04 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1.
Nat.Struct.Mol.Biol., 11, 2004
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1R4B
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1R4C
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1R4F
 | | Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine | | 分子名称: | 3-DEAZA-ADENOSINE, CALCIUM ION, IAG-nucleoside hydrolase | | 著者 | Versees, W, Loverix, S, Vandemeulebroucke, A, Geerlings, P, Steyaert, J. | | 登録日 | 2003-10-06 | | 公開日 | 2004-04-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Leaving group activation by aromatic stacking: an alternative to general Acid catalysis.
J.Mol.Biol., 338, 2004
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1R4I
 | | Crystal Structure of Androgen Receptor DNA-Binding Domain Bound to a Direct Repeat Response Element | | 分子名称: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*AP*AP*GP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*CP*TP*TP*GP*AP*TP*GP*TP*TP*CP*TP*GP*G)-3', Androgen receptor, ... | | 著者 | Shaffer, P.L, Jivan, A, Dollins, D.E, Claessens, F, Gewirth, D.T. | | 登録日 | 2003-10-06 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis of androgen receptor binding to selective androgen response elements.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1R4L
 | | Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) | | 分子名称: | (S,S)-2-{1-CARBOXY-2-[3-(3,5-DICHLORO-BENZYL)-3H-IMIDAZOL-4-YL]-ETHYLAMINO}-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W. | | 登録日 | 2003-10-07 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
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1R4O
 | | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | | 分子名称: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION | | 著者 | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | | 登録日 | 2003-10-07 | | 公開日 | 2003-10-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
Nature, 352, 1991
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1R4P
 | | Shiga toxin type 2 | | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, ... | | 著者 | Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G. | | 登録日 | 2003-10-07 | | 公開日 | 2004-05-11 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
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1R4Q
 | | Shiga toxin | | 分子名称: | SHT cytotoxin A subunit, Shigella toxin chain B | | 著者 | Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G. | | 登録日 | 2003-10-07 | | 公開日 | 2004-05-11 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
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1R4S
 | | URATE OXIDASE FROM ASPERGILLUS FLAVUS COMPLEXED WITH ITS INHIBITOR 9-METHYL URIC ACID | | 分子名称: | 9-METHYL URIC ACID, CYSTEINE, Uricase | | 著者 | Retailleau, P, Colloc'h, N, Prange, T. | | 登録日 | 2003-10-08 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode.
Acta Crystallogr.,Sect.D, 60, 2004
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1R4U
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1R4V
 | | 1.9A crystal structure of protein AQ328 from Aquifex aeolicus | | 分子名称: | CACODYLATE ION, Hypothetical protein AQ_328, ZINC ION | | 著者 | Qiu, Y, Tereshko, V, Kim, Y, Zhang, R, Collart, F, Joachimiak, A, Kossiakoff, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2003-10-08 | | 公開日 | 2004-03-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold.
Proteins, 62, 2006
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1R4W
 | | Crystal structure of Mitochondrial class kappa glutathione transferase | | 分子名称: | GLUTATHIONE, Glutathione S-transferase, mitochondrial | | 著者 | Ladner, J.E, Parsons, J.F, Rife, C.L, Gilliland, G.L, Armstrong, R.N. | | 登録日 | 2003-10-08 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1
Biochemistry, 43, 2004
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1R4X
 | | Crystal Structure Analys of the Gamma-COPI Appendage domain | | 分子名称: | Coatomer gamma subunit, MAGNESIUM ION | | 著者 | Watson, P.J, Frigerio, G, Collins, B.M, Duden, R, Owen, D.J. | | 登録日 | 2003-10-09 | | 公開日 | 2003-10-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
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1R4Z
 | | Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor | | 分子名称: | Lipase, [(4R)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL]METHYL HYDROGEN HEX-5-ENYLPHOSPHONATE | | 著者 | Droege, M.J, Van Pouderoyen, G, Vrenken, T.E, Rueggeberg, C.J, Reetz, M.T, Dijkstra, B.W, Quax, W.J. | | 登録日 | 2003-10-09 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Directed Evolution of Bacillus subtilis Lipase A by Use of Enantiomeric Phosphonate Inhibitors: Crystal Structures and Phage Display Selection
Chembiochem, 7, 2005
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1R50
 | | Bacillus subtilis lipase A with covalently bound Sc-IPG-phosphonate-inhibitor | | 分子名称: | Lipase, [(4S)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL]METHYL HYDROGEN HEX-5-ENYLPHOSPHONATE | | 著者 | Droege, M.J, Van Pouderoyen, G, Vrenken, T.E, Rueggeberg, C.J, Reetz, M.T, Dijkstra, B.W, Quax, W.J. | | 登録日 | 2003-10-09 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Directed Evolution of Bacillus subtilis Lipase A by Use of Enantiomeric Phosphonate Inhibitors: Crystal Structures and Phage Display Selection
Chembiochem, 7, 2005
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1R51
 | | URATE OXIDASE FROM ASPERGILLUS FLAVUS COMPLEXED WITH ITS INHIBITOR 8-AZAXANTHIN | | 分子名称: | 8-AZAXANTHINE, CYSTEINE, Uricase | | 著者 | Prange, T, Retailleau, P, Colloc'h, N. | | 登録日 | 2003-10-09 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode.
Acta Crystallogr.,Sect.D, 60, 2004
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1R52
 | | Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae | | 分子名称: | Chorismate synthase | | 著者 | Quevillon-Cheruel, S, Leulliot, N, Meyer, P, Graille, M, Bremang, M, Blondeau, K, Sorel, I, Poupon, A, Janin, J, van Tilbeurgh, H. | | 登録日 | 2003-10-09 | | 公開日 | 2003-12-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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1R53
 | | Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae | | 分子名称: | Chorismate synthase | | 著者 | Quevillon-Cheruel, S, Leulliot, N, Meyer, P, Graille, M, Bremang, M, Blondeau, K, Sorel, I, Poupon, A, Janin, J, van Tilbeurgh, H. | | 登録日 | 2003-10-09 | | 公開日 | 2003-12-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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1R54
 | | Crystal structure of the catalytic domain of human ADAM33 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADAM 33, CALCIUM ION, ... | | 著者 | Orth, P, Reicher, P, Wang, W, Prosise, W.W, Yarosh-Tomaine, T, Hammond, G, Xiao, L, Mirza, U.A, Zou, J, Strickland, C, Taremi, S.S. | | 登録日 | 2003-10-09 | | 公開日 | 2004-10-12 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structre of the catalytic domain of human ADAM33
J.Mol.Biol., 335, 2004
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1R55
 | | Crystal structure of the catalytic domain of human ADAM 33 | | 分子名称: | (2S,3R)-N~4~-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-N~1~,2-dihydroxy-3-(2-methylpropyl)butanediamide, ADAM 33, CALCIUM ION, ... | | 著者 | Orth, P, Reichert, P, Wang, W, Prosise, W.W, Yarosh-Tomaine, T, Hammond, G, Xiao, L, Mirza, U.A, Zou, J, Strickland, C, Taremi, S.S, Le, H.V, Madison, V. | | 登録日 | 2003-10-09 | | 公開日 | 2004-10-12 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal structre of the catalytic domain of human ADAM33
J.Mol.Biol., 335, 2004
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1R56
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