7A9H
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![BU of 7a9h by Molmil](/molmil-images/mine/7a9h) | Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis | 分子名称: | 1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | 著者 | Gierse, R.M, Reddem, E, Grooves, M.R. | 登録日 | 2020-09-02 | 公開日 | 2022-03-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | 主引用文献 | First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization. Sci Rep, 12, 2022
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7A9U
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![BU of 7a9u by Molmil](/molmil-images/mine/7a9u) | N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-N-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propanamide | 分子名称: | 1,2-ETHANEDIOL, 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-N-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propanamide, Bromodomain-containing protein 4 | 著者 | Chung, C. | 登録日 | 2020-09-02 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.444 Å) | 主引用文献 | A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands. Angew.Chem.Int.Ed.Engl., 59, 2020
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7A9Y
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![BU of 7a9y by Molmil](/molmil-images/mine/7a9y) | Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | 分子名称: | Cellular retinoic acid-binding protein 1, GLYCEROL, MYRISTIC ACID, ... | 著者 | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7A9Z
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![BU of 7a9z by Molmil](/molmil-images/mine/7a9z) | Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | 分子名称: | 4-[2-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 1 | 著者 | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7AA0
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![BU of 7aa0 by Molmil](/molmil-images/mine/7aa0) | Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | 分子名称: | (~{E})-3-[4-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-6-yl)phenyl]prop-2-enoic acid, Cellular retinoic acid-binding protein 2 | 著者 | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7AA1
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![BU of 7aa1 by Molmil](/molmil-images/mine/7aa1) | Structural comparison of cellular retinoic acid binding proteins I and II in the presence and absence of natural and synthetic ligands | 分子名称: | 4-[2-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 | 著者 | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7AAE
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![BU of 7aae by Molmil](/molmil-images/mine/7aae) | Crystal structure of Human serum albumin in complex with myristic acid at 2.27 Angstrom Resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Albumin, FORMIC ACID, ... | 著者 | Maso, L, Liberi, S, Trande, M, Angelini, A, Cendron, L. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Unveiling the binding mode of perfluorooctanoic acid to human serum albumin. Protein Sci., 30, 2021
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7AAI
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![BU of 7aai by Molmil](/molmil-images/mine/7aai) | Crystal structure of Human serum albumin in complex with perfluorooctanoic acid (PFOA) at 2.10 Angstrom Resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | 著者 | Maso, L, Liberi, S, Trande, M, Angelini, A, Cendron, L. | 登録日 | 2020-09-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Unveiling the binding mode of perfluorooctanoic acid to human serum albumin. Protein Sci., 30, 2021
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7ABF
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![BU of 7abf by Molmil](/molmil-images/mine/7abf) | Human pre-Bact-1 spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-09 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7ABG
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![BU of 7abg by Molmil](/molmil-images/mine/7abg) | Human pre-Bact-1 spliceosome | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7ABZ
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![BU of 7abz by Molmil](/molmil-images/mine/7abz) | Structure of pre-accomodated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-09 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7AC0
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![BU of 7ac0 by Molmil](/molmil-images/mine/7ac0) | |
7AC7
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![BU of 7ac7 by Molmil](/molmil-images/mine/7ac7) | Structure of accomodated trans-translation complex on E. Coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-10 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7ACJ
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![BU of 7acj by Molmil](/molmil-images/mine/7acj) | Structure of translocated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-11 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7ACR
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![BU of 7acr by Molmil](/molmil-images/mine/7acr) | Structure of post-translocated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-11 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7ADZ
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![BU of 7adz by Molmil](/molmil-images/mine/7adz) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the cap portion in extended state. | 分子名称: | Phage tail protein, Putative phage tail sheath protein FI, cap adaptor protein (Algo2), ... | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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7AE0
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![BU of 7ae0 by Molmil](/molmil-images/mine/7ae0) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the sheath-tube module in extended state. | 分子名称: | Phage tail protein, Putative phage tail sheath protein FI | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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7AE4
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![BU of 7ae4 by Molmil](/molmil-images/mine/7ae4) | |
7AEB
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![BU of 7aeb by Molmil](/molmil-images/mine/7aeb) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 6-fold symmetry. | 分子名称: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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7AEF
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![BU of 7aef by Molmil](/molmil-images/mine/7aef) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 3-fold symmetry. | 分子名称: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-23 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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7AEK
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![BU of 7aek by Molmil](/molmil-images/mine/7aek) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the contracted sheath shell. | 分子名称: | Putative phage tail sheath protein FI | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | 登録日 | 2020-09-17 | 公開日 | 2022-02-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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7AEL
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![BU of 7ael by Molmil](/molmil-images/mine/7ael) | alpha 1-antitrypsin (C232S) complexed with GSK716 | 分子名称: | Alpha-1-antitrypsin, SULFATE ION, ~{N}-[(1~{S},2~{R})-1-(3-fluoranyl-2-methyl-phenyl)-1-oxidanyl-pentan-2-yl]-2-oxidanylidene-1,3-dihydroindole-4-carboxamide | 著者 | Chung, C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Development of a small molecule that corrects misfolding and increases secretion of Z alpha 1 -antitrypsin. Embo Mol Med, 13, 2021
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7AET
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![BU of 7aet by Molmil](/molmil-images/mine/7aet) | |
7AEU
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![BU of 7aeu by Molmil](/molmil-images/mine/7aeu) | |
7AEV
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![BU of 7aev by Molmil](/molmil-images/mine/7aev) | |