8XVM
 
 | | Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (3-up state) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | | 登録日 | 2024-01-15 | | 公開日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1
Nat Commun, 2024
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8XXL
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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8XXM
 | | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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8XXN
 | | Cryo-EM structure of the human 43S ribosome with PDCD4 | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | | 登録日 | 2024-01-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
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8XYN
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8XZ7
 | | FGFR1 kinase domain with a covalent inhibitor 10h | | 分子名称: | 5-azanyl-3-[2-[4,6-bis(fluoranyl)-2-methyl-3~{H}-benzimidazol-5-yl]ethynyl]-1-[[3-(prop-2-enoylamino)phenyl]methyl]pyrazole-4-carboxamide, Fibroblast growth factor receptor 1, SULFATE ION | | 著者 | Chen, X.J, Chen, Y.H. | | 登録日 | 2024-01-20 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4-carboxamide derivatives as pan-FGFR covalent inhibitors.
Eur.J.Med.Chem., 275, 2024
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8XZI
 | | Cryo-EM structure of the CMF-019-bound human APLNR-Gi complex | | 分子名称: | (3~{S})-5-methyl-3-[[1-pentan-3-yl-2-(thiophen-2-ylmethyl)benzimidazol-5-yl]carbonylamino]hexanoic acid, Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wang, W, Ji, S, Zhang, Y. | | 登録日 | 2024-01-21 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
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8XZP
 | | Crystal structure of folE riboswitch with 8-CH3 Guanine | | 分子名称: | 2-azanyl-8-methyl-1,9-dihydropurin-6-one, MAGNESIUM ION, RNA (53-MER), ... | | 著者 | Li, C.Y, Ren, A.M. | | 登録日 | 2024-01-21 | | 公開日 | 2024-07-24 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8Y0U
 | | dormant ribosome with STM1 | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S1-A, ... | | 著者 | Du, M, Zeng, F. | | 登録日 | 2024-01-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
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8Y0W
 | | dormant ribosome with eIF5A, eEF2 and SERBP1 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Du, M, Zeng, F. | | 登録日 | 2024-01-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
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8Y0X
 | | Dormant ribosome with SERBP1 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Du, M, Zeng, F. | | 登録日 | 2024-01-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
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8Y22
 | | FGFR1 kinase domain with a covalent inhibitor 9g | | 分子名称: | Fibroblast growth factor receptor 1, SULFATE ION, ~{N}-[4-[[4-azanyl-3-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]phenyl]propanamide | | 著者 | Chen, X.J, Chen, Y.H. | | 登録日 | 2024-01-25 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.792 Å) | | 主引用文献 | Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4-carboxamide derivatives as pan-FGFR covalent inhibitors.
Eur.J.Med.Chem., 275, 2024
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8Y2F
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8Y2G
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8Y2S
 | | P-hydroxybenzoate hydroxylase complexed with 4-hydroxy-3-methylbenzoic acid | | 分子名称: | 3-methyl-4-oxidanyl-benzoic acid, 4-hydroxybenzoate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Hara, K, Hashimoto, H, Matsushita, T, Kishimoto, S, Watanabe, K. | | 登録日 | 2024-01-27 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Functional Enhancement of Flavin-Containing Monooxygenase through Machine Learning Methodology
Acs Catalysis, 14, 2024
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8Y36
 | | cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190. | | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | | 登録日 | 2024-01-28 | | 公開日 | 2024-07-24 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
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8Y37
 | | Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190. | | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | | 登録日 | 2024-01-28 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
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8Y38
 | | Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | | 登録日 | 2024-01-28 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
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8Y39
 | | cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | | 登録日 | 2024-01-28 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
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8Y3O
 | | ASFV p72 in complex with Fab B1 | | 分子名称: | B646L, Heavy chain of B1, Light chain of B1 | | 著者 | Wang, X, Fu, W, Yu, Q. | | 登録日 | 2024-01-29 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
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8Y3P
 | | ASFV p72 in complex with Fab C9 | | 分子名称: | B646L, Heavy chain of C9, Light chain of C9 | | 著者 | Wang, X, Fu, W, Yu, Q. | | 登録日 | 2024-01-29 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
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8Y3Q
 | | ASFV p72 in complex with Fab F11 | | 分子名称: | B646L, Heavy chain of F11, Light chain of F11 | | 著者 | Wang, X, Fu, W, Yu, Q. | | 登録日 | 2024-01-29 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
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8Y3R
 | | ASFV p72 in complex with Fab H3 | | 分子名称: | B646L, Heavy chain of H3, Light chain of H3 | | 著者 | Wang, X, Fu, W, Yu, Q. | | 登録日 | 2024-01-29 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
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8Y46
 | | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | | 著者 | Akagashi, M, Watanabe, S. | | 登録日 | 2024-01-30 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates.
Sci Rep, 14, 2024
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8Y4B
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