7OU1
 
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MP2) | | 分子名称: | 1,2-ETHANEDIOL, L-asparaginase, ZINC ION | | 著者 | Imiolczyk, B, Loch, J.I, Gilski, M, Jaskolski, M. | | 登録日 | 2021-06-10 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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7OU6
 | | Human O-GlcNAc hydrolase in complex with DNJNAc-thiazolidines | | 分子名称: | Protein O-GlcNAcase, ~{N}-[(3~{Z},6~{S},7~{R},8~{R},8~{a}~{S})-7,8-bis(oxidanyl)-3-(phenylmethyl)imino-1,5,6,7,8,8~{a}-hexahydro-[1,3]thiazolo[3,4-a]pyridin-6-yl]ethanamide | | 著者 | Males, A, Davies, G.J, Gonzalez-Cuesta, M, Mellet, C.O, Fernandez, J.M.G, Sidhu, P, Ashmus, R, Busmann, J, Vocadlo, D.J, Foster, L. | | 登録日 | 2021-06-11 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications
J.Am.Chem.Soc., 144, 2022
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7OU8
 | | Human O-GlcNAc hydrolase in complex with DNJNAc-thiazolidines | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, O-GlcNAcase BT_4395, ... | | 著者 | Males, A, Davies, G.J, Gonzalez-Cuesta, M, Mellet, C.O, Fernandez, J.M.G, Sidhu, P, Ashmus, R, Busmann, J, Vocadlo, D.J, Foster, L. | | 登録日 | 2021-06-11 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications
J.Am.Chem.Soc., 144, 2022
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7OUC
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7OUD
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7OUJ
 | | Crystal structure of the flavoprotein monooxygenase RubL from rubromycin biosynthesis | | 分子名称: | (2S)-hexane-1,2,6-triol, 4-HYDROXYPROLINE, CHLORIDE ION, ... | | 著者 | Saleem-Batcha, R, Toplak, M, Teufel, R. | | 登録日 | 2021-06-11 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.573 Å) | | 主引用文献 | Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7OUO
 | | Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation | | 分子名称: | BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3') | | 著者 | Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J. | | 登録日 | 2021-06-12 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.212 Å) | | 主引用文献 | Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation.
Front Mol Biosci, 8, 2021
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7OVA
 | | Crystal structure of an AA9 LPMO | | 分子名称: | (2S)-2-hydroxybutanedioic acid, COPPER (II) ION, Endoglucanase, ... | | 著者 | Males, A, Correa, T.L.R, Murakami, M.T, Walton, P.H, Davies, G.J. | | 登録日 | 2021-06-14 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of an AA9 LPMO
To Be Published
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7OVW
 | | Binding domain of botulinum neurotoxin E in complex with GD1a | | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Neurotoxin type E | | 著者 | Masuyer, G, Stenmark, P. | | 登録日 | 2021-06-15 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E.
Int J Mol Sci, 22, 2021
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7OW7
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7OXP
 | | Cryo-EM structure of yeast Sei1 | | 分子名称: | BJ4_G0032880.mRNA.1.CDS.1,BJ4_G0032880.mRNA.1.CDS.1 | | 著者 | Deme, J.C, Lea, S.M. | | 登録日 | 2021-06-22 | | 公開日 | 2021-10-13 | | 最終更新日 | 2021-10-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex.
Nat Commun, 12, 2021
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7OXR
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7OYA
 | | Cryo-EM structure of the 1 hpf zebrafish embryo 80S ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | 登録日 | 2021-06-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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7OYB
 | | Cryo-EM structure of the 6 hpf zebrafish embryo 80S ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | 登録日 | 2021-06-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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7OYC
 | | Cryo-EM structure of the Xenopus egg 80S ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | 登録日 | 2021-06-24 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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7OYD
 | | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | 登録日 | 2021-06-24 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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7OYK
 | | DNA-binding domain of CggR in complex with the DNA operator | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Central glycolytic genes regulator, ... | | 著者 | Novakova, M, Rezacova, P, Skerlova, J, Brynda, J. | | 登録日 | 2021-06-24 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-11-24 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family.
Acta Crystallogr D Struct Biol, 77, 2021
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7OZ6
 | | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MC) | | 分子名称: | DI(HYDROXYETHYL)ETHER, L-asparaginase, ZINC ION | | 著者 | Gilski, M, Loch, J.I, Imiolczyk, B, Jaskolski, M. | | 登録日 | 2021-06-25 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.757 Å) | | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site.
Nat Commun, 12, 2021
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7OZ8
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7OZ9
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7OZA
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7OZB
 | | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 38. | | 分子名称: | 1,2-ETHANEDIOL, 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol, Fibroblast growth factor receptor 1, ... | | 著者 | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | | 登録日 | 2021-06-27 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
J.Med.Chem., 65, 2022
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7OZC
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7OZD
 | | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 34. | | 分子名称: | 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]benzamide, ... | | 著者 | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | | 登録日 | 2021-06-27 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
J.Med.Chem., 65, 2022
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7OZE
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