7TF8
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7THE
| Structure of RBD directed antibody DH1042 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interface | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 Fab Heavy Chain, DH1042 Fab Light Chain, ... | 著者 | May, A.J, Manne, K, Acharya, P. | 登録日 | 2022-01-10 | 公開日 | 2022-02-16 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
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7THT
| CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 heavy chain, ... | 著者 | Manne, K, May, A, Acharya, P. | 登録日 | 2022-01-12 | 公開日 | 2022-02-16 | 最終更新日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
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7TNW
| Structural and functional impact by SARS-CoV-2 Omicron spike mutations | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Peng, H.Q, Volloch, S.R, Chen, B. | 登録日 | 2022-01-21 | 公開日 | 2022-02-16 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional impact by SARS-CoV-2 Omicron spike mutations. Cell Rep, 39, 2022
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7TO4
| Structural and functional impact by SARS-CoV-2 Omicron spike mutations | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Peng, H.Q, Volloch, S.R, Chen, B. | 登録日 | 2022-01-22 | 公開日 | 2022-02-16 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and functional impact by SARS-CoV-2 Omicron spike mutations. Cell Rep, 39, 2022
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7TOW
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7TVX
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7AU4
| Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 3 | 分子名称: | (3~{S})-6-chloranyl-3'-(1,2-oxazol-3-ylmethyl)spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE | 著者 | Talibov, V.O. | 登録日 | 2020-11-02 | 公開日 | 2022-02-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
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7B2J
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7B2U
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7B5Z
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7B77
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7BIJ
| Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 13 | 分子名称: | (3~{S})-3'-(5-fluoranylpyridin-3-yl)spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE | 著者 | Talibov, V.O. | 登録日 | 2021-01-12 | 公開日 | 2022-02-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
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7E6K
| Viral protease | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, N-(2-phenoxyethyl)methanethioamide, ... | 著者 | Zhao, Y, Zhang, Q, Yang, H.T, Rao, Z.H. | 登録日 | 2021-02-22 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Viral protease To be published
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7NBT
| Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 21 | 分子名称: | 2-(benzotriazol-1-yl)-1-[(4~{S})-4-methyl-6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-yl]ethanone, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE | 著者 | Talibov, V.O. | 登録日 | 2021-01-27 | 公開日 | 2022-02-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
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7NEO
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7O46
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7Q0A
| SARS-CoV-2 Spike ectodomain with Fab FI3A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI3A fab Light chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2021-10-14 | 公開日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
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7QBB
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7TL1
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7TL9
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7TP3
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2 | 分子名称: | CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2022-01-24 | 公開日 | 2022-02-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Sci Transl Med, 14, 2022
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7TP4
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2022-01-24 | 公開日 | 2022-02-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Sci Transl Med, 14, 2022
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7TWF
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7TWG
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