9FCM
 
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9UJ2
 
 | 14-3-3 zeta chimera with the S202R peptide of SARS-CoV-2 N (residues 200-213) | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein zeta/delta,Peptide from Nucleoprotein, DI(HYDROXYETHYL)ETHER | 著者 | Boyko, K.M, Matyuta, I.O, Minyaev, M.E, Perfilova, K.V, Sluchanko, N.N. | 登録日 | 2025-04-16 | 公開日 | 2025-05-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High-resolution structure reveals enhanced 14-3-3 binding by a mutant SARS-CoV-2 nucleoprotein variant with improved replicative fitness. Biochem.Biophys.Res.Commun., 767, 2025
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9ELE
 
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9ELF
 
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9ELG
 
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9ELH
 
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9ELI
 
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9ELN
 
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9ELO
 
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9ELP
 
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9ELQ
 
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9HH5
 
 | Crystal Structure of nsp15 Endoribonuclease from SARS CoV-2 in Complex with Sepantronium (YM-155) | 分子名称: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nsp15 - Uridylate-specific endoribonuclease, ... | 著者 | Chatziefthymiou, S.D, Kolbe, M, Hakanpaeae, J, Labahn, J, Windshuegel, B. | 登録日 | 2024-11-21 | 公開日 | 2025-05-28 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15. Protein Sci., 34, 2025
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9HH6
 
 | Crystal Structure of Nsp15 Endoribonuclease from SARS CoV-2 in Complex with TAS-103 | 分子名称: | 1,2-ETHANEDIOL, 6-[2-(dimethylamino)ethylamino]-3-oxidanyl-indeno[2,1-c]quinolin-7-one, ORF1ab polyprotein, ... | 著者 | Chatziefthymiou, S.D, Kolbe, M, Hakanpaeae, J, Labahn, J, Windshuegel, B. | 登録日 | 2024-11-21 | 公開日 | 2025-05-28 | 実験手法 | SOLUTION SCATTERING (2 Å), X-RAY DIFFRACTION | 主引用文献 | Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15. Protein Sci., 34, 2025
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9IZB
 
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9ELJ
 
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9ELK
 
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9ELL
 
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9ELM
 
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9ML4
 
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9ML5
 
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9ML6
 
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9ML7
 
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9ML8
 
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9ML9
 
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9MRU
 
 | Structural Asymmetry in SARS-CoV-2 Nsp15 Hexamer Important for Catalytic Activity | 分子名称: | Uridylate-specific endoribonuclease nsp15 | 著者 | Ketawala, G.K, Sonowal, M, Schrag, L, Fromme, R, Botha, S, Fromme, P. | 登録日 | 2025-01-08 | 公開日 | 2025-06-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Asymmetry in SARS-CoV-2 Nsp15 Hexamer Important for Catalytic Activity To Be Published
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