8KEH
 
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8Y4C
 | | BA.2.86 S-trimer in complex with Nab XGv280 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XGv280 Heavy chain, ... | | 著者 | Zhu, Q, Liu, P. | | 登録日 | 2024-01-30 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
Signal Transduct Target Ther, 9, 2024
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8YLS
 | | Structure of SARS-CoV-2 Mpro in complex with its degrader | | 分子名称: | (4-methoxyphenyl)methyl ~{N}-[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]carbamate, 3C-like proteinase nsp5 | | 著者 | Feng, Y, Li, W, Cheng, S.H, Li, X.B. | | 登録日 | 2024-03-06 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | The Main Protease Degraders: Potent Broad-Spectrum Agents for Anti-Coronavirus Agents
To Be Published
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8ZER
 | | Crystal structure of the complex of Wuhan SARS-CoV-2 RBD (319-541) with P2C5 nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody P2C5, Spike protein S1, ... | | 著者 | Sluchanko, N.N, Varfolomeeva, L.A, Shcheblyakov, D.V, Logunov, D.Y, Gintsburg, A.L, Popov, V.O, Boyko, K.M. | | 登録日 | 2024-05-06 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis for Evasion of New SARS-CoV-2 Variants from the Potent Virus-Neutralizing Nanobody Targeting the S-Protein Receptor-Binding Domain
Biochemistry Mosc.47, 89, 2024
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8ZES
 | | Crystal structure of the Wuhan SARS-CoV-2 RBD (333-541) complexed with P2C5 nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody P2C5, ... | | 著者 | Sluchanko, N.N, Varfolomeeva, L.A, Shcheblyakov, D.V, Logunov, D.Y, Gintsburg, A.L, Popov, V.O, Boyko, K.M. | | 登録日 | 2024-05-06 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural Basis for Evasion of New SARS-CoV-2 Variants from the Potent Virus-Neutralizing Nanobody Targeting the S-Protein Receptor-Binding Domain
Biochemistry Mosc.47, 89, 2024
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9EO6
 | | SARS-CoV2 major protease in complex with a covalent inhibitor SLL11. | | 分子名称: | 3C-like proteinase nsp5, Inhibitor SLL11, POTASSIUM ION | | 著者 | Moche, M, Lennerstrand, J, Nyman, T, Strandback, E, Akaberi, D. | | 登録日 | 2024-03-14 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Antimicrob.Agents Chemother., 2024
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9EOR
 | | SARS-CoV2 major protease in complex with a covalent inhibitor SLL12. | | 分子名称: | 3C-like proteinase nsp5, Inhibitor SLL12, POTASSIUM ION | | 著者 | Moche, M, Lennerstrand, J, Nyman, T, Strandback, E, Akaberi, D. | | 登録日 | 2024-03-15 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Antimicrob.Agents Chemother., 2024
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9EOX
 | | SARS-CoV2 major protease in covalent complex with a soluble inhibitor. | | 分子名称: | 3C-like proteinase nsp5, POTASSIUM ION, Soluble inhibitor | | 著者 | Moche, M, Lennerstrand, J, Nyman, T, Strandback, E, Akaberi, D. | | 登録日 | 2024-03-15 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Antimicrob.Agents Chemother., 2024
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8AJ1
 | | SARS-CoV-2 Mpro in Complex with RK-107 | | 分子名称: | (2R,3S)-3-[[(2S)-3-cyclopropyl-2-[2-oxidanylidene-3-(phenylcarbamoylamino)pyridin-1-yl]propanoyl]amino]-N-methyl-2-oxidanyl-4-[(3S)-2-oxidanylidenepyrrolidin-3-yl]butanamide, 3C-like proteinase nsp5 | | 著者 | El Kilani, H, Hilgenfeld, R. | | 登録日 | 2022-07-27 | | 公開日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | SARS-CoV-2 Mpro in Complex with RK-107
To Be Published
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8Y4A
 | | BA.2.86 S-trimer in complex with Nab XG2v046 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Zhu, Q, Liu, P. | | 登録日 | 2024-01-30 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
Signal Transduct Target Ther, 9, 2024
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