8U9V

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI101

Summary for 8U9V

• Entry DOI: 10.2210/pdb8u9v/pdb
• Descriptor: 3C-like proteinase nsp5, N-{(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-methyl-N~2~-{[(pyridin-3-yl)methoxy]carbonyl}-L-leucinamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34324.18

Authors

Blankenship, L.R.,Liu, W.R. (deposition date: 2023-09-20, release date: 2024-09-25, Last modification date: 2024-10-09)

• Primary citation: Blankenship, L.R.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)