9AYY
 
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9FGS
 | | SARS-CoV-2 (wuhan variant) Spike protein in complex with the single chain fragment scFv41N (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Single Chain fragment scFv41N, Spike glycoprotein,Fibritin | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of scFv41N in complex with SARS-CoV-2 Spike protein
To Be Published
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9FGT
 | | SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76 (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Single chain fragment scFv76, Spike glycoprotein,Fibritin | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of scFv76 in complex with SARS-CoV-2 Omicron Spike protein
To Be Published
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9FGU
 | | SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76-77 (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, scFv76-77 single chain fragment | | 著者 | Berlinguer, M, Chaves-Sanjuan, A, Milazzo, F.M, Minenkova, O, De Santis, R, Bolognesi, M. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure of scFv76-77 in complex with SARS-CoV-2 Omicron Spike protein
To Be Published
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8C0Y
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8QH0
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8QH1
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8RF2
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 1E7 refined against the anomalous diffraction data | | 分子名称: | 1-benzothiophen-5-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RF3
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7G3 refined against the anomalous diffraction data | | 分子名称: | 2-(1-benzothiophen-3-yl)ethanoic acid, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RF4
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 9D4 refined against the anomalous diffraction data | | 分子名称: | 4-chloranyl-1~{H}-indazol-3-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RF5
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 11A7 refined against the anomalous diffraction data | | 分子名称: | 6-fluoro-1,3-benzothiazol-2-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RF6
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 11A7_AL5 refined against the anomalous diffraction data | | 分子名称: | 6-iodanyl-2,3-dihydro-1,3-benzothiazol-2-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RF8
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 11A7_AL6 refined against the anomalous diffraction data | | 分子名称: | 6-bromanyl-1,3-benzothiazol-2-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RFC
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7H2_AL1 refined against the anomalous diffraction data | | 分子名称: | (1~{R})-1-(4-bromophenyl)ethanamine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RFD
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7H2_AL2 refined against the anomalous diffraction data | | 分子名称: | (1~{R})-1-(4-iodophenyl)ethanamine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RFF
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 6A6 refined against the anomalous diffraction data | | 分子名称: | 1,3-benzothiazol-2-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8UKD
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8UKF
 | | SARS-CoV-2 Omicron-EG.5 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-EG.5) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Zhang, Q.E, Acharya, P. | | 登録日 | 2023-10-12 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.
Mol.Cell, 84, 2024
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8XBF
 | | Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with antibody O5C2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, O5C2, heavy chain, ... | | 著者 | Hsu, H.F, Wu, M.H, Chang, Y.C, Hsu, S.T.D. | | 登録日 | 2023-12-06 | | 公開日 | 2024-06-19 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody.
JCI Insight, 9, 2024
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8XXW
 | | Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, M2-7-Heavy chain, M2-7-Light chain, ... | | 著者 | Liu, C, Xie, Y. | | 登録日 | 2024-01-19 | | 公開日 | 2024-06-19 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses.
Cell Rep, 43, 2024
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8YAX
 | | SARS-CoV-2 DMV nsp3-4 pore complex (full-pore) | | 分子名称: | Non-structural protein 4, Papain-like protease nsp3 | | 著者 | Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. | | 登録日 | 2024-02-10 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
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8YB5
 | | SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C6 symmetry) | | 分子名称: | Non-structural protein 4, Papain-like protease nsp3 | | 著者 | Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. | | 登録日 | 2024-02-11 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
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8YB7
 | | SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C3 symmetry) | | 分子名称: | Non-structural protein 4, Papain-like protease nsp3 | | 著者 | Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. | | 登録日 | 2024-02-12 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
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9EOW
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8T7Y
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