8RF3

Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7G3 refined against the anomalous diffraction data

This is a non-PDB format compatible entry.

Summary for 8RF3

• Entry DOI: 10.2210/pdb8rf3/pdb
• Descriptor: Host translation inhibitor nsp1, 2-(1-benzothiophen-3-yl)ethanoic acid (3 entities in total)
• Functional Keywords: viral protein, sars-cov-2, non-structural protein 1, nsp1, fragment hit, anomalous diffraction, protein binding
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 13301.39

Authors

Ma, S.,Damfo, S.,Mykhaylyk, V.,Kozielski, F. (deposition date: 2023-12-12, release date: 2024-06-19)

• Primary citation: Ma, S.,Damfo, S.,Bowler, M.W.,Mykhaylyk, V.,Kozielski, F.; High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.; Acta Crystallogr D Struct Biol, 80:451-463, 2024; PubMed: 38841886; DOI: 10.1107/S2059798324004480

Experimental method

X-RAY DIFFRACTION (1.23 Å)