登録情報 データベース : PDB / ID : 4d0m 構造の表示 ダウンロードとリンクタイトル Phosphatidylinositol 4-kinase III beta in a complex with Rab11a-GTP- gamma-S and the Rab-binding domain of FIP3 要素PHOSPHATIDYLINOSITOL 4-KINASE BETA RAB11 FAMILY-INTERACTING PROTEIN 3 RAS-RELATED PROTEIN RAB-11A 詳細キーワード SIGNALING PROTEIN / PHOSPHOINOSITIDE (ホスファチジルイノシトール) / PHOSPHATIDYLINOSITOL 4-KINASE / LIPID KINASE (キナーゼ) / FAMILY OF RAB INTERACTING PROTEINS / FIP3 / RAB-BINDING DOMAIN / RBD / RAB11 / GTP / PIK93 / GOLGI / RECYCLING ENDOSOME機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
postsynaptic recycling endosome membrane / regulation of early endosome to recycling endosome transport / regulation of protein localization to centrosome / regulation of multivesicular body size / 1-phosphatidylinositol 4-kinase / 1-phosphatidylinositol 4-kinase activity / regulation of endocytic recycling / postsynaptic recycling endosome / establishment of protein localization to organelle / plasma membrane to endosome transport ... postsynaptic recycling endosome membrane / regulation of early endosome to recycling endosome transport / regulation of protein localization to centrosome / regulation of multivesicular body size / 1-phosphatidylinositol 4-kinase / 1-phosphatidylinositol 4-kinase activity / regulation of endocytic recycling / postsynaptic recycling endosome / establishment of protein localization to organelle / plasma membrane to endosome transport / establishment of vesicle localization / negative regulation of adiponectin secretion / regulation of cilium assembly / exosomal secretion / amyloid-beta clearance by transcytosis / rough endoplasmic reticulum membrane / melanosome transport / astral microtubule organization / VxPx cargo-targeting to cilium / neurotransmitter receptor transport, endosome to postsynaptic membrane / Synthesis of PIPs at the Golgi membrane / regulation of vesicle-mediated transport / RAB geranylgeranylation / myosin V binding / protein localization to cilium / multivesicular body assembly / phosphatidylinositol biosynthetic process / dynein light intermediate chain binding / endocytic recycling / phosphatidylinositol-mediated signaling / establishment of protein localization to membrane / protein localization to cell surface / TBC/RABGAPs / syntaxin binding / mitotic metaphase chromosome alignment / lysosome organization / 細胞結合 / positive regulation of epithelial cell migration / エキソサイトーシス / inner ear development / 分裂溝 / phosphatidylinositol phosphate biosynthetic process / endocytic vesicle / centriolar satellite / mitotic spindle assembly / phagocytic vesicle / 小胞 / vesicle-mediated transport / Anchoring of the basal body to the plasma membrane / positive regulation of G2/M transition of mitotic cell cycle / receptor-mediated endocytosis / 中心小体 / エンドソーム / 低分子量GTPアーゼ / G protein activity / 14-3-3 protein binding / trans-Golgi network membrane / regulation of cytokinesis / Translocation of SLC2A4 (GLUT4) to the plasma membrane / protein localization to plasma membrane / ゴルジ体 / cytoplasmic vesicle membrane / recycling endosome / small GTPase binding / Vasopressin regulates renal water homeostasis via Aquaporins / 紡錘体 / recycling endosome membrane / neuron projection development / endocytic vesicle membrane / midbody / cytoplasmic vesicle / microtubule binding / vesicle / mitochondrial outer membrane / molecular adaptor activity / エンドソーム / 細胞周期 / 細胞分裂 / リン酸化 / ゴルジ体 / intracellular membrane-bounded organelle / GTPase activity / 中心体 / glutamatergic synapse / calcium ion binding / protein-containing complex binding / GTP binding / perinuclear region of cytoplasm / ゴルジ体 / シグナル伝達 / protein homodimerization activity / protein-containing complex / ミトコンドリア / extracellular exosome / 核質 / ATP binding / 生体膜 / identical protein binding / 細胞質基質 / 細胞質 類似検索 - 分子機能 Rab-binding domain FIP-RBD / FIP-RBD, C-terminal domain superfamily / FIP domain / FIP-RBD domain profile. / : / PI4KB/PIK1, accessory (PIK) domain / small GTPase Rab1 family profile. / Phosphoinositide 3-kinase, accessory (PIK) domain / Phosphatidylinositol kinase / PIK helical domain profile. ... Rab-binding domain FIP-RBD / FIP-RBD, C-terminal domain superfamily / FIP domain / FIP-RBD domain profile. / : / PI4KB/PIK1, accessory (PIK) domain / small GTPase Rab1 family profile. / Phosphoinositide 3-kinase, accessory (PIK) domain / Phosphatidylinositol kinase / PIK helical domain profile. / Phosphatidylinositol 3- and 4-kinases signature 1. / Phosphatidylinositol 3/4-kinase, conserved site / Phosphatidylinositol 3- and 4-kinases signature 2. / Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily / Phosphoinositide 3-kinase, catalytic domain / Phosphatidylinositol 3- and 4-kinase / Phosphatidylinositol 3- and 4-kinases catalytic domain profile. / Phosphatidylinositol 3-/4-kinase, catalytic domain / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / 低分子量GTPアーゼ / 低分子量GTPアーゼ / EF-hand domain pair / Rab subfamily of small GTPases / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Small GTP-binding protein domain / Protein kinase-like domain superfamily / P-loop containing nucleoside triphosphate hydrolase 類似検索 - ドメイン・相同性 Chem-093 / 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE / Rab11 family-interacting protein 3 / Ras-related protein Rab-11A / Phosphatidylinositol 4-kinase beta 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 6 Å 詳細データ登録者 Burke, J.E. / Inglis, A.J. / Perisic, O. / Masson, G.R. / McLaughlin, S.H. / Rutaganira, F. / Shokat, K.M. / Williams, R.L. 引用ジャーナル : Science / 年 : 2014タイトル : Structures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.著者 : Burke, J.E. / Inglis, A.J. / Perisic, O. / Masson, G.R. / Mclaughlin, S.H. / Rutaganira, F. / Shokat, K.M. / Williams, R.L. 履歴 登録 2014年4月29日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2014年5月28日 Provider : repository / タイプ : Initial release改定 1.1 2014年6月11日 Group : Database references改定 1.2 2014年6月18日 Group : Derived calculations改定 1.3 2018年6月20日 Group : Advisory / Data collection / Derived calculationsカテゴリ : pdbx_struct_conn_angle / pdbx_unobs_or_zero_occ_residues ... pdbx_struct_conn_angle / pdbx_unobs_or_zero_occ_residues / pdbx_validate_close_contact / pdbx_validate_symm_contact / struct_conn / struct_conn_type Item : _struct_conn_type.id改定 1.4 2018年11月21日 Group : Advisory / Data collection / Derived calculationsカテゴリ : pdbx_validate_close_contact / pdbx_validate_symm_contact ... pdbx_validate_close_contact / pdbx_validate_symm_contact / struct_conn / struct_conn_type 改定 1.5 2023年12月20日 Group : Advisory / Data collection ... Advisory / Data collection / Database references / Derived calculations / Other / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_conn_angle / pdbx_unobs_or_zero_occ_residues / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_asym_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_label_asym_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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