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Structure paper

TitleStructures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.
Journal, issue, pagesScience, Vol. 344, Page 1035-, Year 2014
Publish dateApr 29, 2014 (structure data deposition date)
AuthorsBurke, J.E. / Inglis, A.J. / Perisic, O. / Masson, G.R. / Mclaughlin, S.H. / Rutaganira, F. / Shokat, K.M. / Williams, R.L.
External linksScience / PubMed:24876499
MethodsX-ray diffraction
Resolution2.94 - 6 Å
Structure data

PDB-4d0l:
Phosphatidylinositol 4-kinase III beta-PIK93 in a complex with Rab11a- GTP gammaS
Method: X-RAY DIFFRACTION / Resolution: 2.94 Å

PDB-4d0m:
Phosphatidylinositol 4-kinase III beta in a complex with Rab11a-GTP- gamma-S and the Rab-binding domain of FIP3
Method: X-RAY DIFFRACTION / Resolution: 6.0 Å

Chemicals

ChemComp-093:
N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE

ChemComp-GSP:
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER / Water

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/HYDROLASE / TRANSFERASE-HYDROLASE COMPLEX / TRANSFERASE / PHOSPHATIDYLINOSITOL 4-KINASE / PI4K / NUCLEOTIDE / GTP / RAB11 / PIK93 / SIGNALING / GTPASE / SIGNAL TRANSDUCTION / GOLGI / RECYCLING ENDOSOME / PI4P / PHOSPHOINOSITIDE / PTDINS4P / PI4KB / SIGNALING PROTEIN / LIPID KINASE / FAMILY OF RAB INTERACTING PROTEINS / FIP3 / RAB-BINDING DOMAIN / RBD

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