- PDB-3wkj: The nucleosome containing human TSH2B -
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基本情報
登録情報
データベース: PDB / ID: 3wkj
タイトル
The nucleosome containing human TSH2B
要素
DNA (145-MER)
Histone H2A type 1-B/E
Histone H2B type 1-A
Histone H3.1ヒストンH3
Histone H4ヒストンH4
キーワード
STRUCTURAL PROTEIN/DNA (構造) / histone variant / histone-fold / DNA binding protein (DNA結合タンパク質) / STRUCTURAL PROTEIN-DNA complex (構造)
機能・相同性
機能・相同性情報
sperm DNA condensation / nucleosome disassembly / mononuclear cell migration / female germ cell nucleus / plasminogen activation / chromosome organization / negative regulation of megakaryocyte differentiation / protein localization to CENP-A containing chromatin / Chromatin modifying enzymes / Replacement of protamines by nucleosomes in the male pronucleus ...sperm DNA condensation / nucleosome disassembly / mononuclear cell migration / female germ cell nucleus / plasminogen activation / chromosome organization / negative regulation of megakaryocyte differentiation / protein localization to CENP-A containing chromatin / Chromatin modifying enzymes / Replacement of protamines by nucleosomes in the male pronucleus / CENP-A containing nucleosome / epigenetic regulation of gene expression / Packaging Of Telomere Ends / Recognition and association of DNA glycosylase with site containing an affected purine / Cleavage of the damaged purine / Deposition of new CENPA-containing nucleosomes at the centromere / Recognition and association of DNA glycosylase with site containing an affected pyrimidine / Cleavage of the damaged pyrimidine / Inhibition of DNA recombination at telomere / Meiotic synapsis / telomere organization / RNA Polymerase I Promoter Opening / Interleukin-7 signaling / SUMOylation of chromatin organization proteins / Assembly of the ORC complex at the origin of replication / DNAメチル化 / Condensation of Prophase Chromosomes / HCMV Late Events / Chromatin modifications during the maternal to zygotic transition (MZT) / ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression / SIRT1 negatively regulates rRNA expression / PRC2 methylates histones and DNA / Defective pyroptosis / HDACs deacetylate histones / RNA Polymerase I Promoter Escape / Nonhomologous End-Joining (NHEJ) / Transcriptional regulation by small RNAs / Formation of the beta-catenin:TCF transactivating complex / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function / Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 / NoRC negatively regulates rRNA expression / G2/M DNA damage checkpoint / B-WICH complex positively regulates rRNA expression / HDMs demethylate histones / DNA Damage/Telomere Stress Induced Senescence / Metalloprotease DUBs / PKMTs methylate histone lysines / RMTs methylate histone arginines / 遺伝的組換え / Pre-NOTCH Transcription and Translation / nucleosome assembly / Activation of anterior HOX genes in hindbrain development during early embryogenesis / HCMV Early Events / Transcriptional regulation of granulopoiesis / structural constituent of chromatin / UCH proteinases / ヌクレオソーム / E3 ubiquitin ligases ubiquitinate target proteins / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks / 遺伝子発現 / RUNX1 regulates transcription of genes involved in differentiation of HSCs / chromatin organization / Factors involved in megakaryocyte development and platelet production / Processing of DNA double-strand break ends / HATs acetylate histones / histone binding / Senescence-Associated Secretory Phenotype (SASP) / Oxidative Stress Induced Senescence / Estrogen-dependent gene expression / chromosome, telomeric region / Ub-specific processing proteases / cadherin binding / 炎症 / Amyloid fiber formation / protein heterodimerization activity / negative regulation of cell population proliferation / 細胞膜 / protein-containing complex / DNA binding / RNA binding / extracellular exosome / extracellular region / 核質 / 生体膜 / 細胞核 類似検索 - 分子機能
A: Histone H3.1 B: Histone H4 C: Histone H2A type 1-B/E D: Histone H2B type 1-A E: Histone H3.1 F: Histone H4 G: Histone H2A type 1-B/E H: Histone H2B type 1-A I: DNA (145-MER) J: DNA (145-MER) ヘテロ分子