+Open data
-Basic information
Entry | Database: PDB / ID: 6ulv | ||||||
---|---|---|---|---|---|---|---|
Title | BRD4-BD1 in complex with the cyclic peptide 4.2_1 | ||||||
Components |
| ||||||
Keywords | TRANSCRIPTION/INHIBITOR / BET / bromodomain / macrocyclic peptide / BRD4 / inhibitor / RaPID / TRANSCRIPTION-INHIBITOR complex / TRANSCRIPTION | ||||||
Function / homology | Amanitin/phalloidin toxin / toxin activity / IODIDE ION / Alpha-amanitin proprotein 1 Function and homology information | ||||||
Biological species | Homo sapiens (human) synthetic construct (others) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.2 Å | ||||||
Authors | Patel, K. / Walshe, J.L. / Walport, L.J. / Mackay, J.P. | ||||||
Funding support | Australia, 1items
| ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2020 Title: Cyclic peptides can engage a single binding pocket through highly divergent modes. Authors: Patel, K. / Walport, L.J. / Walshe, J.L. / Solomon, P.D. / Low, J.K.K. / Tran, D.H. / Mouradian, K.S. / Silva, A.P.G. / Wilkinson-White, L. / Norman, A. / Franck, C. / Matthews, J.M. / Guss, ...Authors: Patel, K. / Walport, L.J. / Walshe, J.L. / Solomon, P.D. / Low, J.K.K. / Tran, D.H. / Mouradian, K.S. / Silva, A.P.G. / Wilkinson-White, L. / Norman, A. / Franck, C. / Matthews, J.M. / Guss, J.M. / Payne, R.J. / Passioura, T. / Suga, H. / Mackay, J.P. | ||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 6ulv.cif.gz | 268.1 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb6ulv.ent.gz | 179.7 KB | Display | PDB format |
PDBx/mmJSON format | 6ulv.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6ulv_validation.pdf.gz | 778.6 KB | Display | wwPDB validaton report |
---|---|---|---|---|
Full document | 6ulv_full_validation.pdf.gz | 781 KB | Display | |
Data in XML | 6ulv_validation.xml.gz | 21.5 KB | Display | |
Data in CIF | 6ulv_validation.cif.gz | 30.1 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ul/6ulv ftp://data.pdbj.org/pub/pdb/validation_reports/ul/6ulv | HTTPS FTP |
-Related structure data
Related structure data | 6u4aC 6u61C 6u6kC 6u6lC 6u71C 6u72C 6u74C 6u8gC 6u8hC 6u8iC 6u8mC 6ulpC 6ulqC 6ultC 4lyiS S: Starting model for refinement C: citing same article (ref.) |
---|---|
Similar structure data |
-Links
-Assembly
Deposited unit |
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 |
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Unit cell |
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
|