- PDB-6ejx: The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 ... -
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基本情報
登録情報
データベース: PDB / ID: 6ejx
タイトル
The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 integrin Mac-1 I-domain promiscuously and competitively binds multiple ligands in the regulation of Leukocyte function
要素
Platelet glycoprotein Ib alpha chain
キーワード
BLOOD CLOTTING / Gp1balpha / Mac-1
機能・相同性
機能・相同性情報
GP1b-IX-V activation signalling / Platelet Aggregation (Plug Formation) / Intrinsic Pathway of Fibrin Clot Formation / Platelet Adhesion to exposed collagen / glycoprotein Ib-IX-V complex / positive regulation of leukocyte tethering or rolling / blood coagulation, intrinsic pathway / hemostasis / positive regulation of platelet activation / megakaryocyte development ...GP1b-IX-V activation signalling / Platelet Aggregation (Plug Formation) / Intrinsic Pathway of Fibrin Clot Formation / Platelet Adhesion to exposed collagen / glycoprotein Ib-IX-V complex / positive regulation of leukocyte tethering or rolling / blood coagulation, intrinsic pathway / hemostasis / positive regulation of platelet activation / megakaryocyte development / fibrinolysis / release of sequestered calcium ion into cytosol / extracellular matrix / cell morphogenesis / blood coagulation / cell adhesion / external side of plasma membrane / cell surface / extracellular space / membrane / plasma membrane 類似検索 - 分子機能
解像度: 2→49.22 Å / Cor.coef. Fo:Fc: 0.963 / Cor.coef. Fo:Fc free: 0.942 / SU B: 4.459 / SU ML: 0.119 / 交差検証法: THROUGHOUT / ESU R: 0.153 / ESU R Free: 0.149 / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS