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- PDB-4znf: HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FING... -
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Open data
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Basic information
Entry | Database: PDB / ID: 4znf | ||||||
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Title | HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FINGER FROM A HUMAN ENHANCER BINDING PROTEIN IN SOLUTION | ||||||
![]() | ZINC FINGER | ||||||
![]() | ZINC FINGER DNA BINDING DOMAIN | ||||||
Function / homology | ![]() BMP signaling pathway / DNA-binding transcription repressor activity, RNA polymerase II-specific / sequence-specific double-stranded DNA binding / nuclear body / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / mitochondrion ...BMP signaling pathway / DNA-binding transcription repressor activity, RNA polymerase II-specific / sequence-specific double-stranded DNA binding / nuclear body / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / mitochondrion / nucleoplasm / nucleus / metal ion binding / cytosol Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | SOLUTION NMR | ||||||
![]() | Gronenborn, A.M. / Clore, G.M. / Omichinski, J.G. | ||||||
![]() | ![]() Title: High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. Authors: Omichinski, J.G. / Clore, G.M. / Appella, E. / Sakaguchi, K. / Gronenborn, A.M. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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PDBx/mmCIF format | ![]() | 447.3 KB | Display | ![]() |
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PDB format | ![]() | 374.5 KB | Display | ![]() |
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-Validation report
Summary document | ![]() | 341.1 KB | Display | ![]() |
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Full document | ![]() | 582 KB | Display | |
Data in XML | ![]() | 27.4 KB | Display | |
Data in CIF | ![]() | 44.7 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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Atom site foot note | 1: THE C-TERMINAL TWO RESIDUES, LYS 29 AND LYS 30, ARE ILL-DEFINED. | |||||||||
NMR ensembles |
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Components
#1: Protein/peptide | Mass: 3569.212 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() |
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#2: Chemical | ChemComp-ZN / |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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Processing
Refinement | Software ordinal: 1 Details: THE 3D STRUCTURE OF THE ZINC FINGER IN SOLUTION BY NMR IS BASED ON 487 APPROXIMATE INTERPROTON DISTANCE RESTRAINTS AND 63 TORSION ANGLE RESTRAINTS DERIVED FROM NOE AND COUPLING CONSTANT ...Details: THE 3D STRUCTURE OF THE ZINC FINGER IN SOLUTION BY NMR IS BASED ON 487 APPROXIMATE INTERPROTON DISTANCE RESTRAINTS AND 63 TORSION ANGLE RESTRAINTS DERIVED FROM NOE AND COUPLING CONSTANT MEASUREMENTS. THE STRUCTURES ARE CALCULATED USING THE HYBRID METRIC MATRIX DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING METHOD DESCRIBED BY M. NILGES, G. M. CLORE, AND A. M. GRONENBORN (1988) FEBS LETT 229, 317. THIS ENTRY REPRESENTS 41 MODELS OF THE ZINC FINGER OF HUMAN ENHANCER BINDING PROTEIN. THE RESTRAINED MINIMIZED AVERAGE STRUCTURE (SA)$R DERIVED BY RESTRAINED LEAST SQUARE REFINEMENT OF THE MEAN STRUCTURE OBTAINED BY AVERAGING THE COORDINATES OF THE FINAL 41 SA STRUCTURES BEST FITTED TO EACH OTHER CAN BE FOUND IN PDB ENTRY 3ZNF. |
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NMR ensemble | Conformers submitted total number: 41 |