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Yorodumi- PDB-3znf: HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FING... -
+Open data
-Basic information
Entry | Database: PDB / ID: 3znf | ||||||
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Title | HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF A SINGLE ZINC FINGER FROM A HUMAN ENHANCER BINDING PROTEIN IN SOLUTION | ||||||
Components | ZINC FINGER | ||||||
Keywords | ZINC FINGER DNA BINDING DOMAIN | ||||||
Function / homology | Function and homology information BMP signaling pathway / DNA-binding transcription repressor activity, RNA polymerase II-specific / sequence-specific double-stranded DNA binding / nuclear body / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / mitochondrion ...BMP signaling pathway / DNA-binding transcription repressor activity, RNA polymerase II-specific / sequence-specific double-stranded DNA binding / nuclear body / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / mitochondrion / nucleoplasm / nucleus / metal ion binding / cytosol Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Gronenborn, A.M. / Clore, G.M. / Omichinski, J.G. | ||||||
Citation | Journal: Biochemistry / Year: 1990 Title: High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution. Authors: Omichinski, J.G. / Clore, G.M. / Appella, E. / Sakaguchi, K. / Gronenborn, A.M. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 3znf.cif.gz | 22.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb3znf.ent.gz | 12.7 KB | Display | PDB format |
PDBx/mmJSON format | 3znf.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 3znf_validation.pdf.gz | 288.1 KB | Display | wwPDB validaton report |
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Full document | 3znf_full_validation.pdf.gz | 287.8 KB | Display | |
Data in XML | 3znf_validation.xml.gz | 2.3 KB | Display | |
Data in CIF | 3znf_validation.cif.gz | 2.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/zn/3znf ftp://data.pdbj.org/pub/pdb/validation_reports/zn/3znf | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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Atom site foot note | 1: THE C-TERMINAL TWO RESIDUES, LYS 29 AND LYS 30, ARE ILL-DEFINED. | |||||||||
NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 3569.212 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / References: UniProt: P15822 |
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#2: Chemical | ChemComp-ZN / |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Processing
Refinement | Software ordinal: 1 Details: THE 3D STRUCTURE OF THE ZINC FINGER IN SOLUTION BY NMR IS BASED ON 487 APPROXIMATE INTERPROTON DISTANCE RESTRAINTS AND 63 TORSION ANGLE RESTRAINTS DERIVED FROM NOE AND COUPLING CONSTANT ...Details: THE 3D STRUCTURE OF THE ZINC FINGER IN SOLUTION BY NMR IS BASED ON 487 APPROXIMATE INTERPROTON DISTANCE RESTRAINTS AND 63 TORSION ANGLE RESTRAINTS DERIVED FROM NOE AND COUPLING CONSTANT MEASUREMENTS. THE STRUCTURES ARE CALCULATED USING THE HYBRID METRIC MATRIX DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING METHOD DESCRIBED BY M. NILGES, G. M. CLORE, AND A. M. GRONENBORN (1988) FEBS LETT 229, 317. THIS ENTRY REPRESENTS THE RESTRAINED MINIMIZED AVERAGE STRUCTURE (SA)$R DERIVED BY RESTRAINED LEAST SQUARE REFINEMENT OF THE MEAN STRUCTURE OBTAINED BY AVERAGING THE COORDINATES OF THE FINAL 41 SA STRUCTURES BEST FITTED TO EACH OTHER. THE ENTIRE SET OF 41 MODELS CAN BE FOUND IN PDB ENTRY 4ZNF. THE FIELD IN THIS ENTRY THAT OCCUPIES COLUMNS 61 - 66 (RESERVED FOR B-VALUES IN X-RAY CRYSTALLOGRAPHIC ENTRIES) GIVES THE AVERAGE RMS DIFFERENCE BETWEEN THE INDIVIDUAL SA STRUCTURES AND THE MEAN STRUCTURE. |
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NMR ensemble | Conformers submitted total number: 1 |