登録情報 データベース : PDB / ID : 4u30 構造の表示 ダウンロードとリンクタイトル Human mesotrypsin complexed with bikunin Kunitz domain 2 要素 詳細 キーワード HYDROLASE/HYDROLASE INHIBITOR / serine protease / protease inhibitor / protein-protein interaction / protein degradation / proteolysis / substrate specificity / enzyme kinetics / HYDROLASE-HYDROLASE INHIBITOR complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Oxidoreductases; Acting on NADH or NADPH; With a heme protein as acceptor / calcium oxalate binding / Uptake of dietary cobalamins into enterocytes / IgA binding / heme catabolic process / negative regulation of immune response / negative regulation of JNK cascade / Differentiation of keratinocytes in interfollicular epidermis in mammalian skin / antimicrobial humoral response / Alpha-defensins ... Oxidoreductases; Acting on NADH or NADPH; With a heme protein as acceptor / calcium oxalate binding / Uptake of dietary cobalamins into enterocytes / IgA binding / heme catabolic process / negative regulation of immune response / negative regulation of JNK cascade / Differentiation of keratinocytes in interfollicular epidermis in mammalian skin / antimicrobial humoral response / Alpha-defensins / zymogen activation / Antimicrobial peptides / endothelial cell migration / trypsin / calcium channel inhibitor activity / Scavenging of heme from plasma / digestion / serine-type peptidase activity / female pregnancy / serine-type endopeptidase inhibitor activity / tertiary granule lumen / carbohydrate binding / nuclear membrane / collagen-containing extracellular matrix / mitochondrial inner membrane / blood microparticle / oxidoreductase activity / cell adhesion / serine-type endopeptidase activity / calcium ion binding / heme binding / Neutrophil degranulation / cell surface / endoplasmic reticulum / protein homodimerization activity / proteolysis / extracellular space / extracellular exosome / extracellular region / plasma membrane / cytosol 類似検索 - 分子機能 Protein AMBP / Alpha-1-microglobulin / Pancreatic trypsin inhibitor Kunitz domain / Factor Xa Inhibitor / Lipocalin family conserved site / Proteinase inhibitor I2, Kunitz, conserved site / Pancreatic trypsin inhibitor (Kunitz) family signature. / BPTI/Kunitz family of serine protease inhibitors. / Pancreatic trypsin inhibitor Kunitz domain / Kunitz/Bovine pancreatic trypsin inhibitor domain ... Protein AMBP / Alpha-1-microglobulin / Pancreatic trypsin inhibitor Kunitz domain / Factor Xa Inhibitor / Lipocalin family conserved site / Proteinase inhibitor I2, Kunitz, conserved site / Pancreatic trypsin inhibitor (Kunitz) family signature. / BPTI/Kunitz family of serine protease inhibitors. / Pancreatic trypsin inhibitor Kunitz domain / Kunitz/Bovine pancreatic trypsin inhibitor domain / Pancreatic trypsin inhibitor (Kunitz) family profile. / Pancreatic trypsin inhibitor Kunitz domain superfamily / : / Lipocalin / cytosolic fatty-acid binding protein family / Lipocalin/cytosolic fatty-acid binding domain / Calycin / Few Secondary Structures / Irregular / Serine proteases, trypsin family, histidine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Trypsin-like serine protease / Lipocalin signature. / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Beta Barrel / Mainly Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 解像度 : 2.5 Å 詳細データ登録者 Wang, R. / Soares, A.S. / Radisky, E.S. 引用ジャーナル : J.Biol.Chem. / 年 : 2014タイトル : Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN.著者 : Pendlebury, D. / Wang, R. / Henin, R.D. / Hockla, A. / Soares, A.S. / Madden, B.J. / Kazanov, M.D. / Radisky, E.S. 履歴 登録 2014年7月18日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2014年10月15日 Provider : repository / タイプ : Initial release改定 1.1 2014年11月12日 Group : Database references改定 1.2 2014年12月10日 Group : Database references改定 1.3 2015年1月7日 Group : Database references改定 1.4 2023年12月27日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description / Source and taxonomy カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / citation / database_2 / entity_src_gen / pdbx_database_status / pdbx_struct_oper_list / refine_hist / struct_conn / struct_ref_seq_dif Item : _citation.journal_id_CSD / _database_2.pdbx_DOI ... _citation.journal_id_CSD / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _entity_src_gen.pdbx_alt_source_flag / _pdbx_database_status.pdb_format_compatible / _pdbx_struct_oper_list.symmetry_operation / _refine_hist.number_atoms_solvent / _refine_hist.number_atoms_total / _refine_hist.pdbx_number_atoms_ligand / _refine_hist.pdbx_number_atoms_nucleic_acid / _refine_hist.pdbx_number_atoms_protein / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ref_seq_dif.details
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