登録情報 データベース : PDB / ID : 4dvr 構造の表示 ダウンロードとリンクタイトル Crystal structure of YU2 gp120 core in complex with Fab 48d and NBD-557 要素Envelope glycoprotein gp120 Fab 48d Heavy chain Fab 48d Light chain 詳細キーワード IMMUNE SYSTEM/TRANSCRIPTION INHIBITOR / HIV-1 gp120 / CD4 binding site / NBD-557 / IMMUNE SYSTEM-TRANSCRIPTION INHIBITOR complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Dectin-2 family / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / viral protein processing / fusion of virus membrane with host plasma membrane / virus-mediated perturbation of host defense response / fusion of virus membrane with host endosome membrane ... Dectin-2 family / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / viral protein processing / fusion of virus membrane with host plasma membrane / virus-mediated perturbation of host defense response / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / host cell plasma membrane / structural molecule activity / virion membrane / membrane 類似検索 - 分子機能 HIV Envelope Protein Gp120; Chain G / Human immunodeficiency virus 1, Gp160, envelope glycoprotein / Envelope glycoprotein Gp160 / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Envelope glycoprotein GP120 / Human immunodeficiency virus 1, envelope glycoprotein Gp120 / Beta Complex / Immunoglobulins ... HIV Envelope Protein Gp120; Chain G / Human immunodeficiency virus 1, Gp160, envelope glycoprotein / Envelope glycoprotein Gp160 / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Envelope glycoprotein GP120 / Human immunodeficiency virus 1, envelope glycoprotein Gp120 / Beta Complex / Immunoglobulins / Immunoglobulin-like / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性生物種 Human immunodeficiency virus type 1 group M subtype B (ヒト免疫不全ウイルス)Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.5 Å 詳細データ登録者 Kwon, Y.D. / Kwong, P.D. 引用ジャーナル : Plos One / 年 : 2014タイトル : Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.著者 : Kwon, Y.D. / Lalonde, J.M. / Yang, Y. / Elban, M.A. / Sugawara, A. / Courter, J.R. / Jones, D.M. / Smith, A.B. / Debnath, A.K. / Kwong, P.D. 履歴 登録 2012年2月23日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2013年2月27日 Provider : repository / タイプ : Initial release改定 1.1 2014年3月19日 Group : Database references改定 1.2 2014年12月17日 Group : Non-polymer description改定 1.3 2017年5月31日 Group : Structure summary改定 1.4 2020年7月29日 Group : Data collection / Derived calculations / Structure summaryカテゴリ : chem_comp / entity ... chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_site / struct_site_gen Item : _chem_comp.name / _chem_comp.type ... _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation改定 1.5 2021年5月19日 Group : Source and taxonomy / Structure summary / カテゴリ : chem_comp / entity_src_genItem : _chem_comp.pdbx_synonyms / _entity_src_gen.gene_src_common_name ... _chem_comp.pdbx_synonyms / _entity_src_gen.gene_src_common_name / _entity_src_gen.host_org_common_name / _entity_src_gen.pdbx_host_org_cell_line / _entity_src_gen.pdbx_host_org_strain 改定 1.6 2023年9月13日 Group : Advisory / Data collection ... Advisory / Data collection / Database references / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_atoms Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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