- PDB-4awn: Structure of recombinant human DNase I (rhDNaseI) in complex with... -
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Basic information
Entry
Database: PDB / ID: 4awn
Title
Structure of recombinant human DNase I (rhDNaseI) in complex with Magnesium and Phosphate.
Components
DEOXYRIBONUCLEASE-1
Keywords
HYDROLASE / ENDONUCLEASE / PULMOZYME
Function / homology
Function and homology information
: / regulation of neutrophil mediated cytotoxicity / regulation of acute inflammatory response / deoxyribonuclease I / DNA nuclease activity / neutrophil activation involved in immune response / deoxyribonuclease I activity / DNA catabolic process / nuclear envelope / actin binding ...: / regulation of neutrophil mediated cytotoxicity / regulation of acute inflammatory response / deoxyribonuclease I / DNA nuclease activity / neutrophil activation involved in immune response / deoxyribonuclease I activity / DNA catabolic process / nuclear envelope / actin binding / apoptotic process / DNA binding / extracellular exosome / extracellular region / nucleus Similarity search - Function
Deoxyribonuclease I / Deoxyribonuclease I, active site / Deoxyribonuclease I, conservied site / Deoxyribonuclease I signature 2. / Deoxyribonuclease I signature 1. / deoxyribonuclease I / Deoxyribonuclease I; Chain A / Endonuclease/exonuclease/phosphatase / Endonuclease/exonuclease/phosphatase / Endonuclease/Exonuclease/phosphatase family ...Deoxyribonuclease I / Deoxyribonuclease I, active site / Deoxyribonuclease I, conservied site / Deoxyribonuclease I signature 2. / Deoxyribonuclease I signature 1. / deoxyribonuclease I / Deoxyribonuclease I; Chain A / Endonuclease/exonuclease/phosphatase / Endonuclease/exonuclease/phosphatase / Endonuclease/Exonuclease/phosphatase family / Endonuclease/exonuclease/phosphatase superfamily / 4-Layer Sandwich / Alpha Beta Similarity search - Domain/homology
DEOXYRIBONUCLEASE-1 / DEOXYRIBONUCLEASE I / DNASE I / DORNASE ALFA
Mass: 29277.879 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) HOMO SAPIENS (human) / Cell line (production host): CHO / Production host: CRICETULUS GRISEUS (Chinese hamster) / References: UniProt: P24855, deoxyribonuclease I